Pragmatic Patient Choice-Driven Radical Treatment Approach (PRAGRAD) for Very Advanced Unresectable Oral Cavity Cancers.

Purpose: The treatment of locally advanced unresectable oral cavity cancers (OCCs) is challenging, with limited consensus on optimal management and poor outcomes. Our clinical practice identified a subset of unresectable OCC patients who respond favorably to aggressive alternate treatment with chemotherapy and radiation therapy. We propose a systematic design for optimal selection method that is patient choice-driven while attempting to managing unresectable OCC with radical therapy approach.

Age-related cortical changes and cognitive performance in healthy adults.

Aging is a continuous process with cortical thinning as a common consequence. This study aimed to evaluate cortical thickness, volume and area differences associated with age in healthy population. Seventy-six healthy individuals were divided into three age groups: younger (25-40 years, n = 25), middle-aged (41-55 years, n = 24), and older (56-80 years, n = 27).

Unique roll clouds along the flow path of the Indian summer monsoon low-level jet over the Arabian sea.

Unique boundary layer roll clouds in the form of parallel straight lines are formed along the flow path of the Arabian Sea branch (ASB) of the Indian summer monsoon low-level jet. An attempt has been made in this study to understand the mechanism behind their formation using high-resolution NOAA-20 satellite imageries and ECMWF reanalysis data. Thermal and dynamical instabilities generated by the ASB of the low-level jet in the atmospheric boundary layer produce eddies in the primary flow of the ASB which organize themselves as counter rotating roll vortices.

How Effective is Deep Inspiration Breath Hold in Minimizing Cardiac Doses During Hybrid Radiotherapy Treatment for Left-Sided Breast Cancer with Comprehensive Regional Nodes?

Background: In the context of left breast cancer radiotherapy, long term cardiopulmonary toxicity has been well-documented, significant efforts have been undertaken to mitigate such toxicity by using 4D gating, deep inspiration breath-hold(DIBH) and active breath control(ABC) techniques.

Purpose: To evaluate and compare the cardio-pulmonary radiation doses incurred during postmastectomy radiotherapy (PMRT) in two distinct breathing conditions such as DIBH and Free Breathing (FB), with a specific focus on the left chest wall with comprehensive regional nodal irradiation.

Materials And Methods: A prospective dosimetric study was conducted on 15 patients who received adjuvant loco-regional radiotherapy of chest-wall (CW), supraclavicular fossa(SCF), and internal mammary region(IMC), with or without axilla.

Nano-catalytic behavior of CeO nanoparticles in dye adsorption: Synthesis through bio-combustion and assessment of UV-light-driven photo-adsorption of indigo carmine dye.

This study explores the adsorption of indigo carmine dye using bio-combusted cerium oxide nanoparticles (CeO NPs). CeO NPs were synthesized using a bio-combustion method, and then subjected to structural, morphological, and optical characterization for thorough investigation. Structural investigation was carried out using X-ray diffraction (XRD), which revealed a cubic structure with evaluated average crystallite size of 11.