Laparoscopic Roux-en-Y hepaticojejunostomy for post-cholecystectomy type IIIb benign biliary stricture with internal duodenal fistula: A case report with surgical video.

Laparoscopic cholecystectomy (LC) is a widely performed procedure, but it can be complicated by iatrogenic bile duct injuries, leading to benign biliary strictures (BBS). This report details the case of a 38-year-old man with a Bismuth type IIIb BBS and an internal duodenal fistula following LC. He underwent a totally laparoscopic Roux-en-Y hepaticojejunostomy (RYHJ), a technically demanding procedure, particularly in the presence of complex biliary strictures.

Outcomes of near-infrared fluorescence guided colonic interposition for corrosive esophageal stricture.

Introduction: Colonic interposition is the most commonly performed surgery for high corrosive esophageal or combined esophagogastric strictures. Here, we present the outcomes of colonic interposition using a modified right colonic graft and the utility of indocyanine green-guided fluorescence imaging.

Methods: We retrospectively reviewed the medical records of 30 patients with corrosive esophageal strictures who underwent colon interposition surgery between July 2017 and December 2023.

Twenty-four-hour pH monitoring of gastric conduit in post-esophagectomy patients: correlation with clinical and endoscopic parameters in a prospective cohort study from India.

Purpose: Esophagectomy for malignancy leads to decreased gastric conduit acidity due to bilateral vagotomy and fundic gland area reduction. However, reflux symptoms occur. The changes in pH of gastric conduit and esophageal remnant post-esophagectomy were studied and correlated clinically, endoscopically and with positivity.

Anti-IL-4Rα aptamer reduces IL-4 signalling and formation of nasal polyps.

Background: Aptamers are RNA- or DNA-based oligomers with high protein-specific binding properties that have demonstrated effectiveness in targeting various proteins and treating diseases such as cancer. However, their application in regulating chronic respiratory diseases, such as chronic rhinosinusitis, is not well established.

Methods: In this study, we used the anti-IL-4Rα aptamer (anti-IL-4Rα apt) to investigate its impact on IL-4 signalling and related T-helper 2 (Th2)-type inflammation in nasal polyp tissue.

Solitary Renal Metastasis in Esophageal Squamous Cell Cancer Detected on F-18 FDG PET/CT - A Rare Presentation.

Positron emission tomography with computed tomography using fluorine-18 fluoro-D-glucose positron emission tomography-computed tomography (F-18 FDG PET/CT) is routinely used for baseline staging and response assessment for esophageal squamous cell cancer (E-SCC). Metastases in E-SCC are usually seen in regional lymph nodes and lungs with solitary metastases to the kidney being extremely rare. We present a case of solitary unilateral renal metastasis detected on baseline F-18 FDG PET/CT in an otherwise operable E-SCC.