Myokines, important signalling molecules in regulation of homeostasis in a post-injury state, have not been studied in burn patients. Here, we aimed to analyse dynamic changes in systemic and local concentrations of myokines and evaluated their associations with the mode of physiotherapy in burn patients. In this pilot study, 20 burn patients underwent repeated functional proprioceptive stimulation and conventional physiotherapy.
View Article and Find Full Text PDFEpidemiol Mikrobiol Imunol
August 2025
Background And Aim: High voltage electrotrauma is one of the most serious injuries we can encounter in modern medicine, often associated with multiple disabilities and high susceptibility to infectious complications. These patients are admitted to specialized burn centers and require extensive multidisciplinary collaboration. In this study, we aim to uncover the prevalence, types and characteristics of microbial infections that develop in the aftermath of high voltage electrotrauma and to identify risk factors that may contribute to patients' susceptibility to infections.
View Article and Find Full Text PDFThis study explores the innovative approach in the development of freeze-dried hydrogel films, leveraging the unique properties of gum Karaya (GK), poly-(vinyl alcohol) (PVA), poly-(ethylene glycol) (PEG), and glycerol with a coating of octenidine dihydrochloride (OCT). These innovative hydrogel films exhibit at a certain glycerol concentration a sandwich-like structure, achieved through a tailored freeze-drying process, which enhances transparency and mechanical stability. OCT provides superior antibacterial performance, effectively combating multidrug-resistant bacteria with a controlled and gradual release mechanism, surpassing conventional OCT solutions that require frequent reapplication for infected wound treatment without the creation of bacterial resistance.
View Article and Find Full Text PDFBackground: Lymphovenous anastomosis (LVA) and vascularized lymph node transfer (VLNT) are both accepted microsurgical treatment options for lymphedema. This article summarises and analyses recent data on outcomes associated with LVA and VLNT for lymphedema treatment at varying degrees of severity.
Methods: Literature research was conducted in the PubMed and Embase Ovid database to extract articles published through March 2024.
Klin Mikrobiol Infekc Lek
March 2024
Introduction: Staphylococcus aureus is a gram-positive, facultatively anaerobic coccus capable of causing infectious diseases in animals and humans. Especially dangerous are multidrug-resistant forms with poor or even no response to available treatments.
Objectives: The study aimed to verify the effect of enzybiotics on the healing of S.