Posterior Decompression and Arthrodesis in Congenital Atlantoaxial Subluxation and Associated Complex Vertebral Artery Anomaly: A Case Report.

Introduction: The overall incidence of vertebral artery (VA) variations is 2-3%, but among patients with congenital anomalies at the cranio-vertebral junction, it is 20%. Knowing these anomalies is important, if failed to recognize can lead to VA injury during surgery and subsequent cerebrovascular accidents.

Case Report: A 14-year-old boy presenting with progressive weakness of bilateral upper limb and lower limb was diagnosed as case of supra-axial cervical myelopathy due to congenital atlantoaxial subluxation with fenestration of VA and high-riding VA.

Influence of non-coplanar arcs in stereotactic ablative radiotherapy of Liver: A clinician's plan acceptance based comparative analysis between Ring gantry and C- Arm linear accelerators.

This study aims to evaluate the dosimetric compatibility of coplanar-only arc plans from a ring gantry linear accelerator with coplanar and non-coplanar arc-based plans from C-arm linear accelerators for liver stereotactic ablative radiotherapy (SABR). Halcyon (HAL) is a ring gantry, while Novalis Tx (NTx) and TrueBeam STx (TB) are C-arm linear accelerators. A total of 40 liver stereotactic ablative radiotherapy (SABR) patients, with either primary disease or metastasis, were planned using these three competing linear accelerators.

A chlorinated diketopiperazine antibiotic targets .

We describe a novel macrocyclic peptide, speirobactin, produced by that selectively kills . A nonribosomal peptide synthase containing two linear modules codes for the synthesis of speirobactin. The biosynthetic operon contains a pentapeptide-repeat protein as a resistance gene.

Regulation of Notch signaling by multiple Ankyrin repeat containing protein Mask.

Background: Notch pathway is an evolutionarily conserved, highly pleiotropic signaling system that governs diverse developmental processes. Its diverse functions are attributed to the intricate regulatory mechanisms that finely tune the pathway. While several known elements contribute to maintaining cellular homeostasis by modulating Notch signaling, many unidentified components likely play significant roles in its regulation, necessitating further exploration.