Factors affecting the development of hydrocephalus in patients with spinal neural tube defects.

Aim: We conducted this study to determine the factors that could prevent formation of spina bifida (11) and the causes of hydrocephalus, which show an important association.

Material And Methods: We retrospectively evaluated the data of 51 patients with spina bifida (11) who were operated at Şanlıurfa Training and Research Hospital between December 2021 and October 2022.

Results: The mean folate level of the mothers was 7.

Comparison of the Results of Microsurgical Techniques in Lumbar Disc Herniation: A Retrospective Analysis.

Background: When surgical intervention is required for lumbar disc herniation, microdiscectomy is frequently employed. Although sequestrectomy has been compared in several aspects, there is limited evidence regarding clinical outcomes. In this study, we aimed to analyze the clinical effectiveness of both techniques by focusing on their postoperative results.

Prognostic Role of the Naples Score in Extensive-Stage Small Cell Lung Cancer: A Missed Opportunity in Inflammation-Based Stratification.

The Naples Prognostic Score (NPS) is a composite inflammation-nutrition index whose prognostic value has been scarcely examined in extensive-stage small cell lung cancer (ES-SCLC). This study aimed to evaluate the prognostic significance of the NPS in this setting. A retrospective analysis was performed on 142 patients diagnosed with ES-SCLC between March 2014 and June 2024.

Investigation of the effects of MTHFR gene variations and homocysteine levels in hypertensive patients.

Objective: To investigate the effects of methylenetetrahydrofolate reductase (MTHFR) gene C677T/A1298C polymorphisms on serum homocysteine levels and hypertension.

Methods: Venous blood samples were collected in EDTA tubes from patients and controls (80 hypertensive patients and 67 healthy controls) and genomic DNA was isolated. The polymorphisms of MTHFR C677T and A1298C were identified using the polymerase chain reaction (PCR) and restriction fragment length polymorphisms (RFLP) technique.

Adrenergic signaling coordinates distant and local responses to amputation in axolotl.

Many species regenerate lost body parts following amputation. Most limb regeneration research has focused on the immediate injury site. Meanwhile, body-wide injury responses remain largely unexplored but may be critical for regeneration.