Advancing outcome measure development and analytical approaches: Pain in Animals Workshop 2023.

Annually, millions of humans and animals suffer from chronic and acute pain, creating welfare and quality of life concerns for both humans and animals who suffer this pain. In developing new therapeutic approaches, the challenge is to accurately measure this pain to ascertain the efficacy of novel therapeutics. Additionally, there is a need to develop new and effective analgesic options that may offer alternatives to using opioids that contribute to the opioid epidemic.

Physical Activity Monitors in Companion Animal Chronic Pain Research-A Review Focused on Osteoarthritis Pain.

Accelerometry-based physical activity monitors (PAMs) are a useful tool to collect objective measurements of physical activity and movement. Recently, there has been an increased utilization of PAMs in companion animal chronic pain research. However, a general lack of understanding of PAMs contributes to challenges and misconceptions around the interpretation and utility of these data.

Force Plate Gait Analysis in Dogs After Femoral Head and Neck Excision.

Femoral head and neck excision (FHNE) remains a common orthopedic surgical procedure in many countries. However, data on postoperative outcomes regarding changes in hindlimb function are limited. This study aimed to evaluate hindlimb function after FHNE in dogs of different weights.

Comparison of lidocaine incisional block techniques on early postoperative pain scores in dogs undergoing ovariohysterectomy.

Objective: To compare postoperative pain scores following lidocaine incisional block techniques (infiltration versus splash methods) with an intraperitoneal splash block in dogs undergoing ovariohysterectomy.

Study Design: Prospective, randomized, double-blinded, clinical study.

Animals: A total of 30 client-owned female dogs.

Global pharmacovigilance reporting of the first monoclonal antibody for canine osteoarthritis: a case study with bedinvetmab (Librela™).

Introduction: Continuous product monitoring post approval builds on the knowledge gained during clinical studies to aid in understanding a product's safety and efficacy profile. Pharmacovigilance reporting of a medicinal product might be influenced by several factors including duration in the market, geographical region and veterinary practices. The goals of this report are to present the global data accrued for bedinvetmab, the first monoclonal antibody for canine osteoarthritis, and to explore reporting patterns globally and across major markets.