Tailored magnetic transitions and magnetocaloric properties towards room temperature in LaBiSrMnO ( = 0.05-0.25) manganites.

A series of Bi-doped manganites, , LaBiSrMnO ( = 0.05, 0.1, 0.

An Annotated Biobank of Triple-Negative Breast Cancer Patient-Derived Xenografts Features Treatment-Naïve and Longitudinal Samples During Neoadjuvant Chemotherapy.

Triple-negative breast cancer (TNBC) that fails to respond to neoadjuvant chemotherapy (NACT) can be lethal. Developing effective strategies to eradicate chemoresistant disease requires experimental models that recapitulate the heterogeneity characteristic of TNBC. To that end, we established a biobank of 92 orthotopic patient-derived xenograft (PDX) models of TNBC from the tumors of 75 patients enrolled in the ARTEMIS clinical trial (NCT02276443), including 12 longitudinal sets generated from serial patient biopsies collected throughout NACT treatment and from metastatic disease.

Effect of Postural Training and Core Strengthing Exercise Anlong with Interferential Therapy on Low Back Pain in Household Workers.

Objective: The aim of the study is to know the effectiveness of postural training and core strengthening exercises along with interferential therapy on low back pain for household workers.

Background Of The Study: Pain in the lower back area that can be related to problems with the lumbar spine. This may be due to changing work environment, including the nature of long sitting work hours.

Moving From Point-Based Analysis to Systems-Based Modeling: Knowledge Integration to Address Antimicrobial Resistance.

Optimizing antibiotic therapy requires a holistic bench-to-bedside approach with interdisciplinary collaboration between pharmacologists, clinicians, microbiologists, and computational scientists. Novel experimental models provide insights into drug-pathogen interactions within complex host environments, while multiomics data provide details of the molecular mechanisms shaping bacterial responses. Pharmacometrics and machine learning can be used to integrate these insights into in silico models.