[Perioperative complications in surgery for craniosynostosis in children: a systematic review and meta-analysis].

Objective: To study the structure, incidence and risk factors of perioperative complications in children with craniosynostosis (CS).

Material And Methods: A systematic searching of data was performed for analysis of perioperative complications and adverse events following surgical correction of CS in patients younger 24 months.

Results.

Prospective assessment of surgical stress response in patients with craniosynostosis: comparison of clinical and laboratory data.

Background: Highly traumatic surgical correction of craniosynostosis (CS) is usually followed by severe postoperative period and high risk of complications. Surgical stress response (SSR) is an important and often neglected cause of severe early postoperative period.

Objective: To compare clinical and laboratory parameters of SSR in children who underwent various surgeries for CS.

[Prospective analysis of inflammatory markers and perioperative clinical data in children with craniosynostosis undergoing reconstructive surgery].

Background: Craniosynostosis (CS) is a group of skull malformations manifested by congenital absence or premature closure of cranial sutures. Reconstructive surgery in the second half of life is traditional approach for CS. The issues of surgical stress response after reconstructive surgery for CS in children are still unclear.

[Reset osmostat syndrome - when hyponatremia become «a normal»: diagnostics, case report].

Reset osmostat syndrome (ROS) is characterized by a change of normal plasma osmolality threshold (decrease or increase), which leads to chronic dysnatremia (hypo- or hypernatremia). We have described a clinical case of ROS and chronic hyponatremia in a patient with chordoid glioma of the III ventricle. It is known that the patient had previously been diagnosed with hyponatremia (131-134 mmol/l).

[Delta-He a new biomarker for a surgical clinic].

Background: Delta-He the difference between hemoglobin content in reticulocytes and erytrocytes is a relatively new laboratory indicator that is easily measured in everyday practice. This parameter is directly related to iron bioavailability for hemoglobin synthesis and can reflect various conditions accompanied by cytokine expression including systemic inflammation.

Objective: To analyze the prospects for practical application of hemoglobin delta in assessment of neurosurgical patients throughout in-hospital treatment.