Health-related quality of life and unmet needs of people with epilepsy and their family caregivers: A systematic scoping review.

Introduction: People with epilepsy can experience limitations in their everyday lives due to their condition, impacting on health-related quality of life (HRQOL). We synthesized evidence on HRQOL and unmet needs in adult people with epilepsy and their family caregivers to provide a comprehensive overview of the impact of epilepsy and to identify opportunities for healthcare service improvements.

Methods: Systematic literature searches were conducted in CINAHL, Embase, Ovid MEDLINE, APA PsychInfo, Scopus, and grey literature databases (12 August 2024).

Ipsilateral foetal-type posterior cerebral artery is associated with cognitive decline after carotid revascularisation.

Background: Stenosis of the internal carotid artery has been associated with cognitive impairment and decline. However, studies testing the effect of carotid revascularisation on cognition have had conflicting results. This may in part be explained by variation in the flow territory of the carotid artery.

Periprocedural hemodynamic depression is associated with a higher number of new ischemic brain lesions after stenting in the International Carotid Stenting Study-MRI Substudy.

Background And Purpose: Carotid artery stenting (CAS) is associated with a higher risk of both hemodynamic depression and new ischemic brain lesions on diffusion-weighted imaging than carotid endarterectomy (CEA). We assessed whether the occurrence of hemodynamic depression is associated with these lesions in patients with symptomatic carotid stenosis treated by CAS or CEA in the randomized International Carotid Stenting Study (ICSS)-MRI substudy.

Methods: The number and total volume of new ischemic lesions on diffusion-weighted imaging 1 to 3 days after CAS or CEA was measured in the ICSS-MRI substudy.

The effect of white matter lesions on cognition after carotid revascularization.

Background: Cerebral white matter lesions (WML) are associated with cognitive impairment, and carotid revascularization with cognitive worsening or improvement. We assessed the relation between WML severity and changes in cognition after carotid endarterectomy or stenting.

Methods: Patients with symptomatic carotid artery stenosis, enrolled in the International Carotid Stenting Study (ISRCTN25337470), underwent detailed neuropsychological examinations (NPEs) before and after 6 months.

Effects of carotid endarterectomy or stenting on hemodynamic complications in the International Carotid Stenting Study: a randomized comparison.

Background: Carotid endarterectomy and carotid artery stenting are frequently complicated by hemodynamic instability.

Aims: The study aims to compare the incidence of hemodynamic complications between carotid artery stenting and carotid endarterectomy in the International Carotid Stenting Study (ISRCTN25337470).

Methods: Patients with symptomatic carotid stenosis were randomly allocated to carotid artery stenting or carotid endarterectomy.

Effects of carotid endarterectomy or stenting on blood pressure in the International Carotid Stenting Study (ICSS).

Background And Purpose: Arterial hypotension is more frequently observed early after carotid artery stenting (CAS) than after carotid endarterectomy (CEA), but their long-term effects on blood pressure (BP) are unclear. We compared the effects of CAS and CEA on BP up to 1 year after treatment in the International Carotid Stenting Study.

Methods: Patients with symptomatic carotid stenosis were randomly allocated to CAS or CEA.