Publications by authors named "Ayman Abdalgader"

Article Synopsis
  • The study examines the combined effects of hyperglycemia and hypoglycemia on intraventricular hemorrhage (IVH) and mortality in very preterm infants admitted to a neonatal intensive care unit from January 2020 to January 2024.
  • Out of 554 infants analyzed, 75.5% experienced hyperglycemia and/or hypoglycemia in their first postnatal week, with IVH occurring in 28.5% of infants and 13.7% resulting in death during the study.
  • The findings indicate that both isolated hyperglycemia and the combination of hypo- and hyperglycemia significantly increase the risk of IVH and correlate with higher mortality rates among these infants.
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Background And Objective: To systematically review, critically appraise the quality of recent clinical practice guidelines (CPGs) for neonatal hypoxic ischemic encephalopathy (HIE), and map their recommendations.

Data Sources: CPG databases (GIN, ECRI, NICE, SIGN, DynaMed), Bibliographic databases (PubMed, Embase, CINAHL), and related specialized professional societies (e.g.

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Background: This study aimed to investigate the relationship between acute kidney injury (AKI) in the first 2 weeks of life and brain injury on term-equivalent age magnetic resonance imaging in very preterm infants.

Methods: We included 116 infants with a birth weight of < 1500 g who were born at the King Saud Medical City at ≤ 32 gestational weeks. They were admitted to the neonatal intensive care unit and underwent term-equivalent age and pre-discharge brain magnetic resonance imaging.

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Growing resistance of microorganisms to antibiotics for the treatment of late-onset sepsis (LOS) in premature infants has led physicians to use antibiotics that are not well studied in neonatal populations. We aimed to determine the efficacy and safety of colistin and fluoroquinolone for the treatment of persistent LOS. We retrospectively reviewed infants with gram-negative LOS, who received either colistin or fluoroquinolone therapy, to determine if there was a significant difference in kidney and liver function tests and electrolyte levels before, during, and at the end of the treatment.

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Background: Intraventricular hemorrhage (IVH) is a serious complication of premature (<32 weeks) deliveries, especially in very-low-birth-weight (VLBW; <1500 g) neonates. Infants developing severe IVH are more prone to long-term developmental disabilities. Although 62%-79% of women in Saudi Arabia receive antenatal steroids, IVH incidence remains high.

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