Multi-layered water resources, management, and uses under the impacts of global changes in a southern coastal metropolis: When will it be already too late? Crossed analysis in Recife, NE Brazil.

Coastal water resources are a worldwide key socio-environmental issue considering the increasing concentration of population in these areas. Here, we propose an integrative transdisciplinary approach of water resource, water management and water access in Recife (NE Brazil). The present-day water situation is conceptualized as an imbricated multi-layered system: a multi-layered water resource, managed by a multi-layered governance system and used by a multi-layered social population.

Origins and processes of groundwater salinization in the urban coastal aquifers of Recife (Pernambuco, Brazil): A multi-isotope approach.

In the coastal multilayer aquifer system of a highly urbanized southern city (Recife, Brazil), where groundwaters are affected by salinization, a multi-isotope approach (Sr, B, O, H) was used to investigate the sources and processes of salinization. The high diversity of the geological bodies, built since the Atlantic opening during the Cretaceous, highly constrains the heterogeneity of the groundwater chemistry, e.g.

Opposing Mcl-1, the GALIG proapoptotic gene is upregulated as neutrophils die and underexpressed in Acute Myeloid Leukemia cells.

GALIG gene expression induces apoptosis in cultured cells through a pathway still under investigation. It is highly expressed in leukocytes but weakly detectable in bone marrow, suggesting a role in the myeloid lineage homeostasis. We show here that GALIG-induced cell death is counteracted by the overexpression of MCL-1, a pro-survival member of the Bcl2 family.