A Phase 3 Multicenter, Double-Blind Study Comparing Efficacy, Safety, Immunogenicity, and Pharmacokinetics of Alkem's Biosimilar Teriparatide Versus Reference Teriparatide in Postmenopausal Osteoporosis.

Objective: The primary purpose of this study was to compare the efficacy and safety of proposed biosimilar teriparatide with reference teriparatide in patients of postmenopausal osteoporosis. The secondary objectives were to assess the pharmacodynamic response of study drugs in postmenopausal osteoporosis and to assess the pharmacokinetic profile of biosimilar and reference teriparatide in a subset of subjects (a total of 30 evaluable subjects i.e.

Challenges and Solutions for Transplantation in Northeast India: Proceedings of the National Organ and Tissue Organization Session at the India Society of Organ Transplantation 2023 Meeting in Kolkata.

Background: India is the third highest in terms of the total number of organ transplants in a year worldwide mainly based on living donor transplants. The number of deceased donor transplants has been limited in India ranking only at the 68th position of 94 countries that reported data to Global Observatory on Organ Donation and Transplantation during the year 2022.

Methods: Representatives of National Organ and Tissue Transplant Organisation in addition to local transplant experts from Northeast India and Indian Society of Organ Transplantation discussed challenges and potential solutions for organ transplantation in Northeast India at the National Organ and Tissue Transplant Organisation session during the India Society of Organ Transplantation 2023 annual conference held at Kolkata.

The Optical Absorption and Electron Paramagnetic Resonance of Cu Incorporated Dicalcium Lead Propionate.

Following γ-ray exposure, a room-temperature study of electron paramagnetic resonance (EPR) is conducted on Cu-doped dicalcium lead propionate (DCLP), CaPb(CHCOO). Cu is found at four magnetically equivalent sites replacing Ca. EPR spectra are fitted to a rhombic symmetry Hamiltonian in order to determine the spin Hamiltonian parameters.

Superposition model study of Cr3+ doped tetra methyl ammonium cadmium chloride.

The zero field splitting parameter D of Cr(3+) doped in tetra methyl ammonium cadmium chloride (TMCC) is calculated with perturbation formula using microscopic spin Hamiltonian theory and crystal field parameters from superposition model. The theoretically calculated ZFS parameter for Cr(3+) in TMCC single crystal is compared with the experimental value obtained by electron paramagnetic resonance (EPR). The local structure distortion is considered to obtain the crystal field parameters.