Publications by authors named "Avinash Nankani"
A clearer vision: insights into juvenile idiopathic arthritis-associated uveitis.
Proc (Bayl Univ Med Cent)
February 2024
The aim of this narrative review is to synthesize existing evidence-based knowledge on juvenile idiopathic arthritis-associated uveitis (JIA-U). We highlight epidemiology, pathophysiology, causes and genetics, risk factors, clinical features, diagnosis and screening, laboratory biomarkers, treatment options, trials with recent advances, and research challenges pertaining to JIA-U. The prevalence of JIA-U varies with different JIA subtypes, most frequently associated with the oligoarticular subtype.
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- The study aimed to compare the incidence of pulmonary barotrauma, a lung injury caused by mechanical ventilation, in COVID-19 patients and those with other respiratory issues.
- Conducted at Aga Khan University Hospital, the research analyzed data from patients on mechanical ventilation between October 2020 and March 2021, dividing them into a COVID-19 group and a control group.
- Results showed a significantly higher incidence of barotrauma in the COVID-19 group (34%) compared to the control group (5.5%), highlighting increased risks for patients with acute respiratory distress syndrome due to COVID-19.
Article Synopsis
- The study compares conservative management and early intervention in asymptomatic patients with severe aortic stenosis using data from 12 studies totaling 3,624 patients.
- Early intervention significantly reduces the risk of various adverse outcomes, including all-cause mortality, cardiac and non-cardiac mortality, heart failure hospitalizations, and major adverse cardiac events.
- No significant differences were found between the two approaches regarding short-term mortality rates (30-day and 90-day) and myocardial infarction.
Correlation Of Computerized Tomography (CT) Severity Score For COVID-19 Pneumonia With Clinical Outcomes.
J Ayub Med Coll Abbottabad
April 2022
Background: Though various computerized tomography (CT) severity scores have been described for risk prognostication for coronavirus disease 2019 (COVID-19), most are challenging to calculate and have variable inter-observer agreement. The objective of this study was to develop a simple CT severity score (CT-SS) with good inter-observer agreement and assess its correlation with clinical outcome.
Methods: This retrospective study was conducted at the Aga Khan University Hospital (AKUH), from April-August 2020.
Introduction: While chest x-rays (CXRs) represent a cost-effective imaging modality for developing countries like Pakistan, their utility for the prognostication of COVID-19 has been minimally explored. Thus, we describe the frequency and distribution of CXR findings, and their association with clinical outcomes of patients with COVID-19.
Methods: All adult (≥ 18 years) patients presenting between 28th February-31st May to the emergency department of a tertiary care hospital in Pakistan, who were COVID-19 positive on RT-PCR with CXR done on presentation, were included.