Publications by authors named "Aurora Paraninfi"
Article Synopsis
- - The study investigates the relationship between flow-mediated dilation (FMD), a measure of endothelial function, and factors like NADPH oxidase type 2 (NOX-2) and lipopolysaccharides (LPS) in patients with COVID-19 pneumonia (CP) compared to those with community acquired pneumonia (CAP) and healthy controls.
- - Results show that patients with CP exhibited higher levels of oxidative stress and inflammation markers (like TNF-α and IL-6) and lower FMD, indicating worsened endothelial function and increased health risks.
- - LPS is identified as a key predictor of FMD in CP patients, suggesting that low-grade endotoxemia in COVID-19 could enhance oxidative stress and
Background: Acutely ill medical patients experience deep venous thrombosis (DVT) during the hospitalization, however the time course of DVT is still unclear.
Objectives: To evaluate risk factors in acutely ill hospitalized medical patients for proximal asymptomatic DVT (ADVT) and symptomatic DVT (SDVT) at admission and discharge.
Patients/methods: In this prospective observational study, consecutive acutely ill medical patients (hospitalized mainly for acute medical disease as infections, neoplasm, anemia, heart failure) underwent compression ultrasonography (CUS) of proximal lower limb veins within 48 h from admission and at discharge to diagnose ADVT and SDVT.
Background: Endothelial dysfunction and oxidative stress were hypothesized to be involved in the pathogenesis of coronary microvascular angina (MVA). NADPH oxidase-2 (NOX2) activation could provoke increased oxidative stress and endothelial dysfunction, but data on MVA have not been provided yet.
Aims: This study aimed to evaluate the interaction among NOX2 activation, serum lipopolysaccharide (LPS) levels, as well as oxidative stress production as potential causes of endothelial dysfunction in MVA patients.
Objective: Endothelial dysfunction and oxidative stress are among the most relevant mechanisms underlying the atherosclerotic process in patients with type 2 diabetes mellitus (T2 DM). Extra virgin olive oil (EVOO) reduces postprandial glycemia with a mechanism counteracting oxidative stress-mediated incretin down-regulation in healthy subjects and in patients with impaired fasting glucose. The aim of this study was to evaluate if the intake of chocolate enriched by EVOO had positive effects on endothelial function and oxidative stress in patients with T2 DM.
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