The aim of this study is to evaluate the differences in tissue levels of oestrogen receptor (ER), progesterone receptor (PR), epidermal growth factor receptor (EGFR) and carbohydrate antigen 15-3 (CA 15-3) in benign and malignant mammary tumours in dogs. A total of 45 tumoural masses taken from 22 dogs with mammary tumours were included in the study. Based on the histopathological results of mammary tissues, study groups were formed as bening tumours (Group BT; n = 15) and malignant tumours (Group MT; n = 30) with Group MT divided into 2 subgroups as malignant epithelial tumours (Group MET; n = 16), carcinosarcomas and malignant mixed tumours (Group MMT; n = 14).
View Article and Find Full Text PDFThe polymorphisms of the PRNP gene influence the susceptibility to scrapie in goats. In this study, caprine PRNP gene was analysed in a total of 249 individuals from three main indigenous goat breeds of Turkey: Anatolian Black, Angora and Kilis. We focused on the Anatolian Black breed, which represents 97% of the goat population in Turkey and compared the data of samples originated from different geographical regions.
View Article and Find Full Text PDFThe aim of this study was to determine the variants of the thioesterase (TE) beta-ketoacyl reductase (KR) domains of the Fatty Acid Synthase (FASN) gene, in the East Anatolian Red (EAR) and South Anatolian Red (SAR) cattle breeds. It has been suggested that the FASN gene is effective on fatty acid composition of meat in cattle. In this study, the genotype and allele frequencies of g.
View Article and Find Full Text PDFThe aim of the study was to investigate the effect of Garcinia cambogia extract on serum calcium (Ca), phosphorus (P), magnesium (Mg), iron (Fe), zinc (Zn) and copper (Cu) concentrations in rats fed with the normal or the high-lipid and -cholesterol diet. Thirty 1-year-old female Sprague-Dawley rats (pathogen-free), weighing an average of 229 g, were randomly assigned to three experimental groups of ten animals each. Diets and tap water were given ad libitum for 75 days.
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