Publications by authors named "Atefeh Barzegari"
Background: Pediatric glioma is a rare condition that can lead to significant mortality and morbidity due to its high recurrence rate. This study is a phase I nonrandomized clinical trial that was conducted to assess the safety, feasibility, and potential efficacy of the intrathecal (IT) injection of multiple doses of allogenic NK cells in pediatric patients with refractory/recurrent gliomas.
Methods: Allogeneic NK cells were isolated from random healthy unrelated donors via positive selection of CD56 + cells.
Article Synopsis
- Primary bone tumors (PBTs) are rare but can lead to significant health risks, particularly due to their tendency to spread to the lungs, affecting survival rates based on tumor type and treatment options.
- Despite progress in treatment over the past 40 years, survival rates for PBT patients have not significantly improved, highlighting the need for new therapies.
- Current treatments include surgery, radiotherapy, and chemotherapy, with new promising immunotherapies like CAR-T cell therapy being explored to enhance patient outcomes in managing PBTs.