Publications by authors named "Asuva Arin"
Article Synopsis
- The study focuses on using natural peptides from the extracellular matrix (ECM) to create alginate derivatives aimed at improving cellular functions.
- Three variations of ECM-conjugated sodium alginate were synthesized and used to fabricate mat scaffolds, which demonstrated enhanced properties as ECM concentration increased.
- In vivo tests showed that the optimized scaffolds (EMAT-2 and EMAT-3) significantly improved liver regeneration and skin healing in rodent models, indicating their potential for clinical applications in wound healing.
This study used a unique approach by developing a bilayer system that can simultaneously accomplish non-adhesion, hemostatic, and tissue regenerative properties. In this system, agarose was used as a carrier material, with an agarose-TEMPO-oxidized cellulose nanofiber (TOCN), (AT) layer acting as a non-adhesion layer and an Agarose-Extracellular matrix, (AE) layer acting as a tissue regenerative layer. Thrombin was loaded on the AE layer as an initiator of the healing process, by hemostasis.
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