Heart rate variability, quality of life, and sleep quality in patients with epilepsy.

Objective: Recent data have shown that patients with epilepsy experience reduced quality of life and poor sleep quality, which are also closely related to heart rate variability. For the first time, we investigated the relationship between heart rate variability and quality of life and sleep in patients with epilepsy.

Methods: Twenty-seven patients with medically controlled epilepsy, 23 patients with drug-resistant epilepsy, and 36 healthy subjects were included in this cross-sectional prospective study.

Serum neurofilament light chain as a potential biomarker in restless legs syndrome: a cross-sectional study.

Objective: Neurofilament light chain (NfL) has emerged as a promising biomarker for several neurological diseases. Therefore, we investigated its serum levels and their association with disease characteristics, including duration, severity, and medication use in patients with restless legs syndrome (RLS).

Method: This cross-sectional prospective study included 71 RLS patients and 70 healthy controls.

Role of vitamin D in the association between pre-stroke sleep quality and poststroke depression and anxiety.

Purpose: Poor sleep quality, mood disorders, and vitamin D deficiency are common in stroke. We investigated the association between serum vitamin D levels and pre-stroke sleep quality and the occurrence of poststroke depression (PSD) and poststroke anxiety (PSA) in acute ischemic stroke (AIS).

Methods: This prospective cross-sectional study included hospitalized patients with AIS and age- and sex-matched controls.

Associations of the neutrophil/lymphocyte ratio, monocyte/ lymphocyte ratio, and platelet/lymphocyte ratio with COVID-19 disease severity in patients with neurological symptoms: A cross-sectional monocentric study.

Objectives: Data are limited regarding the relationship of neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and platelet/ lymphocyte ratio (PLR) with neurological symptoms (NS) in COVID-19 patients. This study is the first to assess the utility of the NLR, MLR, and PLR for predicting COVID-19 severity in infected patients with NS.

Materials And Methods: Consecutive 192 PCR-positive COVID-19 patients with NS were included in this cross-sectional and prospective study.

Neurological symptoms and neuronal damage markers in acute COVID-19: Is there a correlation? A pilot study.

A wide spectrum of neurological symptoms (NS) has been described in patients with COVID-19. We examined the plasma levels of neuron-specific enolase (NSE) and neurofilament light chain (NFL) together, as neuronal damage markers, and their relationships with clinical severity in patients with NS at acute COVID-19. A total of 20 healthy controls and 59 patients with confirmed COVID-19 were enrolled in this pilot prospective study.

Cognitive assessment of patients with nonalcoholic fatty liver disease.

Objective: The aim of this study was to investigate cognitive performance for the first time in participants with nonalcoholic fatty liver disease (NAFLD) using the Montreal Cognitive Assessment (MoCA).

Participants And Methods: In total, 70 participants with NAFLD and 73 age-matched and sex-matched healthy participants were enrolled in this prospective cross-sectional study. The diagnosis of NAFLD was made on the basis of abdominal ultrasonography findings.

Association Between Overactive Bladder and Polyneuropathy in Diabetic Patients.

Purpose: Diabetes mellitus (DM) is a chronic metabolic disorder that often leads to complications. We aimed to correlate two complications of DM, polyneuropathy and hyperactive bladder syndrome, using noninvasive measures, such as screening tests.

Methods: We included 80 female and 40 male type 2 diabetic patients in this prospective study.

Does vitamin D deficiency trigger carpal tunnel syndrome?

Objective: Vitamin D deficiencies are associated with a variety of chronic diseases. The goal of the present study was to investigate the relationship between vitamin D levels and carpal tunnel syndrome (CTS).

Methods: This study included 90 patients with mild to moderate CTS and assessed their routine serum 25-hydroxyvitamin D levels.

Pain, depression and sleep disorders in patients with diabetic and nondiabetic carpal tunnel syndrome: a vicious cycle.

Unlabelled: Carpal tunnel syndrome (CTS) is a condition involving nerve entrapment that often leads to chronic neuropathic pain. We aimed to evaluate sleep quality and related parameters in diabetic and non-diabetic CTS patients.

Method: This study included a total of 366 patients with chronic CTS.

Associations of olfactory bulb and depth of olfactory sulcus with basal ganglia and hippocampus in patients with Parkinson's disease.

Parkinson's disease (PD) is a neurodegenerative disorder characterized by hyposmia in the preclinical stages. We investigated the relationships of olfactory bulb (OB) volume and olfactory sulcus (OS) depth with basal ganglia and hippocampal volumes. The study included 25 patients with PD and 40 age- and sex-matched control subjects.

Cognitive Impairment in Patients with Psoriasis: A Cross-Sectional Study Using the Montreal Cognitive Assessment.

Background: Psoriasis is a multisystem chronic inflammatory disorder that is thought to be associated with cognitive impairment.

Aims: We aimed to investigate cognitive performance using the Montreal Cognitive Assessment (MoCA) in patients with psoriasis.

Methods: In total, 77 patients with psoriasis and 83 age- and sex-matched control subjects were enrolled in this prospective cross-sectional study.

Olfactory bulb and olfactory sulcus depths are associated with disease duration and attack frequency in multiple sclerosis patients.

Background And Purpose: Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disease that progresses to axonal loss and demyelinization. Olfactory dysfunction in patients with MS has been reported frequently. We were interested in the associations of olfactory bulb (OB) and olfactory sulcus depth (OSD) with disease duration and attack frequency.

Retinol-binding protein-4 and hs-CRP levels in patients with migraine.

Retinol-binding protein-4 (RBP4) and high-sensitivity C-reactive protein (hs-CRP) levels are associated with inflammation in patients with migraine. The release of proinflammatory cytokines during migraine results in recurrent sterile neurogenic inflammation. This study aimed to determine the correlation between RBP4 and hs-CRP levels, and migraine, which is considered an inflammatory disease.

Iliac arteriovenous fistula presenting with ascites.

Arteriovenous fistula presents rarely with ascites. Diagnosis, with an elusive clinical presentation, is often incidental or delayed. A 35-year-old woman presented with ascites and cardiac decompensation.

The effects of caffeic acid phenethyl ester on inflammatory cytokines after acute spinal cord injury.

Background: The purpose of this study was to investigate the effects of Caffeic Acid Phenethyl Ester (CAPE) on proinflammatory cytokines, IL-1ß and TNF-α, and explore its healing effect after acute spinal cord injury.

Methods: Forty-eight male Wistar-Albino rats were used in this study which was planned as three groups. All groups were divided into two sub-groups.

The relationship between oxidative stress markers and visual evoked potentials in different hypertension models.

Objective: We aimed to define the influence of different hypertension models on lipid peroxidation markers [conjugated dienes (CD) and thiobarbituric acid-reactive substances (TBARS)], antioxidant protection [paraoxonase-1 (PON1) activity] and visual evoked potential (VEP) changes in rats.

Methods: The study was designed as four different hypertension models. Rats (n=84) were divided equally into six groups: Control group (C), Sham operated (Sham), Two kidney-one clip (2K-1C), One kidney-one clip (1K-1C), Deoxycorticosterone acetate (DOCA) and N-omega-nitro-L-arginine-methyl ester (L-NAME).

The relationship between dry eye and migraine.

Presently, migraine and dry eye are both thought to have an inflammatory pathogenesis. We aimed to investigate dry eye findings and any relationship with headache characteristics in migraine patients with and without aura. In total, 58 migraineurs and 41 age- and gender-matched controls were enrolled in this prospective clinical study.

Serum lipid peroxidation markers are correlated with those in brain samples in different stress models.

Objective: Stress can stimulate increased production of oxygen radicals. We investigated the correlations between serum levels of lipid peroxidation markers and those in brain samples in different stress models.

Methods: Animals (n = 96) were divided equally into eight groups: a control group and groups treated with vitamin E (Vit E); exposed to immobilisation stress; exposed to immobilisation stress and treated with Vit E; exposed to cold stress; exposed to cold stress and treated with Vit E; exposed to both immobilisation and cold stress; and a final group exposed to both immobilisation and cold stress and treated with Vit E.

Evaluation of the chorioretinal thickness changes in Alzheimer's disease using spectral-domain optical coherence tomography.

Background: To assess the chorioretinal thickness changes using spectral-domain optical coherence tomography (SD-OCT) and to evaluate the association between these structural changes and cognitive impairment in Alzheimer's disease (AD).

Design: Prospective, cross-sectional study

Participants: Thirty-one eyes of 31 consecutive patients with AD and 30 eyes of 30 cognitively healthy age-matched control subjects were recruited

Methods: SD-OCT (RTVue-100) was used to measure the macular ganglion cell complex thickness (mGCC), outer retinal thickness (ORL), and the choroidal thickness (CT). Cognitive function was evaluated by Mini-Mental State examination (MMSE) on the same day of the optical examination.