Publications by authors named "Asefa Shariq Ansari"
Tetralogy of Fallot (TOF) is a common congenital heart defect with a traditionally high reintervention rate of post-surgical correction. The Residual Lesion Score (RLS) is a tool used to evaluate the quality of surgical outcomes by assessing postoperative echocardiography findings and the need for unplanned reinterventions. The study assesses the association between the Residual Lesion Score (RLS) and early and midterm outcomes, including reintervention rates, in patients undergoing valve-sparing TOF repair at a tertiary care center in a low- and middle-income country (LMIC).
View Article and Find Full Text PDFArticle Synopsis
- The Omicron variant of SARS-CoV-2 includes various sublineages such as BA.2, BA.2.12.1, BA.4, and BA.5, which are now more prevalent than the earlier BA.1 variant.
- These sublineages have mutations that enhance binding to ACE2, reduce cell fusion capabilities, and significantly lower neutralizing antibody responses from previous infections or vaccines.
- However, booster shots using the original Wuhan-Hu-1 spike sequence can significantly enhance neutralizing antibody levels, suggesting that while initial vaccinations may be less effective against Omicron, boosters can still provide strong protection against severe illness.