Publications by authors named "Aseem R Shukla"

Background: The utilization of robot-assisted laparoscopic pyeloplasty (RALP) for the surgical correction of ureteropelvic junction obstruction (UPJO) continues to increase. The aim of this study was to determine whether robot-assisted laparoscopic pyeloplasty (RALP) is a safe and equally efficacious procedure compared to open pyeloplasty (OP) in infants ≤12 months old.

Methods: All patients ≤12 months old who underwent RALP or OP between January 2012 and January 2021 at five participating centers were included in this study.

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Introduction: Urinary continence is a goal of bladder exstrophy epispadias complex (BEEC) surgical management. However, it is often not achieved until school age or later. Little is known about the mental health implications of this incontinence on caregivers and whether this should affect timing of surgical interventions to achieve continence.

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Objective: To provide a mid-term evaluation-defined as 3 to 10 years of post-operative follow up-of children with duplicated collecting systems undergoing ureteroureterostomy. In addition, a sub stratified analysis based on surgical approach is delivered to compare outcomes between the two approaches.

Materials And Methods: An IRB-approved single-institutional registry was retrospectively reviewed to identify all patients undergoing ureteroureterostomy (UU) for duplex renal anomalies between 2014 and 2020.

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Introduction: Robot-assisted laparoscopic pyeloplasty (RALP) is commonly performed to repair ureteropelvic junction obstruction (UPJO), but concerns remain regarding its efficacy and safety, as well as its cost compared to open pyeloplasty (OP). We hypothesized that primary RALP is equally efficacious to OP, with comparable direct costs.

Methods: An IRB-approved single institutional registry was retrospectively reviewed to identify all patients undergoing primary OP and RALP between July 2012 and March 2020.

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Introduction: Bladder exstrophy-epispadias complex (BEEC) is a devastating congenital anomaly of the urinary tract and is associated with an increased risk of bladder cancer. The etiology of the BEEC is unknown, but a clear genetic component has been highlighted. Currently, all genetic studies suffer from small populations, limited to a European background.

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Introduction: While large and symptomatic urachal anomalies (UAs) often lead to surgical excision, urachal malignancy is rare, rendering prophylactic excision unwarranted. We hypothesize that in the pediatric population, the presentation of an infected UA is the predominant etiology leading to surgical intervention.

Methods: We retrospectively identified patients with UA from July 2012 to December 2021 evaluated in our urology outpatient.

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Ureteropelvic junction obstruction (UPJO) is a common cause of hydronephrosis in the pediatric population. Management with an open dismembered pyeloplasty was first described by Anderson-Hynes in 1949; minimally invasive approaches have been increasingly utilized. In the subsequent text and accompanying video, we review the technique for dismembered robotic assisted laparoscopic pyeloplasty in the pediatric population.

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Dismembered ureteral reimplant (DUR) is done to treat primary obstructive megaureter (POM). To describe and compare outcomes between open dismembered ureteral reimplant (ODUR) robot-assisted laparoscopic dismembered ureteral reimplant (RALDUR). An IRB-approved registry was used to retrospectively identify all patients who underwent DUR for POM between 2015 and 2022.

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Introduction: Robot-assisted Laparoscopic Appendicovesicostomy (RALAPV) is increasingly performed as a minimally invasive alternative to the open appendicovesicostomy (OPAV), but questions remain regarding the efficacy of the RALAPV compared to OPAV.

Objective: To assess and compare outcomes for non-augmented RALAPV to the open surgical approach.

Materials And Methods: An IRB approved prospective registry was retrospectively examined to abstract all patients who underwent APV without augment between 2012 and 2023.

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Article Synopsis
  • Hypospadias repair often leads to complications, and while factors like anatomy and surgeon experience are known contributors, the influence of social determinants of health on outcomes is less understood.
  • The study aimed to explore how resources and community conditions, assessed through the Childhood Opportunity Index (COI), impact post-operative complications in children who underwent distal hypospadias repair.
  • An analysis of 938 patients showed a 14.1% complication rate, but no significant correlations were found between COI, insurance type, race, and complications; however, anatomical factors like glans width and chordee degree were linked to complications.
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Article Synopsis
  • - The study investigates non-operative management of pediatric ureteroceles, finding that this approach leads to less frequent and later secondary surgical interventions compared to those who undergo immediate surgery.
  • - Successful non-operative treatment is linked to factors such as smaller ureterocele size, absence of high-grade vesicoureteral reflux (VUR), and fewer comorbidities among patients.
  • - Despite these findings, there is still no standard method for choosing which patients should receive non-operative care, highlighting the need for more consensus in managing ureteroceles.
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Objective: To investigate whether the panoramic view offered by robot-assisted laparoscopic pyeloplasty (RALP) reduces the likelihood of missing a crossing vessel compared to open pyeloplasty in cases where initial pyeloplasty fails.

Methods: A single institution redo-pyeloplasty database was reviewed for children treated between January 2012 to July 2023. Clinical history, imaging and operative details were reviewed to identify the etiology for the redo procedure.

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Purpose: Bladder exstrophy (BE) poses challenges both during the surgical repair and throughout follow-up. In 2013, a multi-institutional BE consortium was initiated, which included utilization of unified surgical principles for the complete primary repair of exstrophy (CPRE), real-time coaching, ongoing video capture and review of video footage, prospective data collection, and routine patient data analysis, with the goal of optimizing the surgical procedure to minimize devastating complications such as glans ischemia and bladder dehiscence while maximizing the rate of volitional voiding with continence and long-term protection of the upper tracts. This study reports on our short-term complications and intermediate-term continence outcomes.

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Article Synopsis
  • Epispadias is a developmental condition affecting boys, with varying severity and surgical treatment options ranging from simple repair to complex reconstructions of the bladder and urethra.
  • This study evaluated the outcomes of 36 boys with epispadias from three institutions, focusing on their continence status and the type of surgical procedures they received over a median follow-up period of 11.3 years.
  • Results showed that 92% of participants were able to void normally; however, continence rates varied based on the severity of epispadias, with complete dryness reported in 58% of those able to void.
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Article Synopsis
  • * Early detection before birth is crucial for helping families prepare and ensuring that specialized medical resources are in place.
  • * The study highlights a specific case of covered cloacal exstrophy and emphasizes the need for more data across institutions to better understand and support these rare conditions over time.
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Introduction: The use of caudal anesthesia at the time of hypospadias repair remains controversial as some prior studies have reported increased postoperative complication rates associated with caudal nerve block. However, these results have been called into question due to confounding factors and heterogeneous study groups.

Objective: Given the importance of identifying true risk factors associated with increased hypospadias complication rate, we examined our experience with caudal anesthesia limiting our analysis to distal repairs.

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Article Synopsis
  • The opioid crisis has raised concerns about the long-term effects of opioid use in children, prompting research into the safety of ketorolac for pain management in pediatric hypospadias surgery.
  • A study analyzed data from 1,044 patients who underwent hypospadias surgery between 2018 and 2021, finding that ketorolac was used in 37.9% of cases and did not increase post-operative bleeding or unplanned medical encounters.
  • The findings suggest that ketorolac is a safer alternative to opioids for pain management in this population, although the study had limitations including its retrospective nature and challenges in evaluating pain in children.
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Introduction: Caring for children with bladder exstrophy-epispadias complex (BEEC) exacts a long-term emotional toll on caregivers. Previous studies leave a gap in understanding the impact that caring for a child with BEEC has on caregivers in low- and middle-income countries (LMIC). We hypothesize that families and caregivers experience psychological distress that has long gone unaddressed.

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Introduction: Historically, repair of bladder exstrophy (BE) is associated with compromise to the upper tracts; the single stage repair of BE was considered to exacerbate risks of kidney impairment.

Objective: We aim to evaluate the risk of upper urinary tract deterioration or chronic kidney disease after the complete primary repair of exstrophy (CPRE).

Study Design: As part of the U.

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Introduction: The complete primary repair of bladder exstrophy (CPRE) aims to restore normal anatomy through complete mobilization and reapproximation of the bladder neck and proximal urethra.

Methods: The Peña stimulator has previously been used to identify musculature in the pelvis. The device is now used to distinguish intersymphyseal bands from pelvic floor and urethral sphincteric musculature during CPRE.

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