Publications by authors named "Arunaksharan Narayanankutty"

The increasing environmental and health concerns about synthetic pesticides have compelled researchers to investigate more sustainable, plant-based substitutes for pest management. Due to their unique modes of action and biodegradability, essential oils (EOs) represent effective bio-pesticides. This study examines the biological activities of (Asteraceae) EO (AVEO) against Keifer (Eriophyidae), a destructive gall mite on (Fabaceae), using fumigation, contact toxicity, and repellency assays for the first time.

View Article and Find Full Text PDF

Desmodium gyrans DC (Fabaceae) has been widely used in Indian and Chinese traditional medicine as a cardiotonic and for wound healing. There is not much scientific literature supporting the medicinal use of the plant. The present study aimed to evaluate the cardioprotective effect of the methanolic extract of D.

View Article and Find Full Text PDF

Inflammation is a physiological condition that when unattended causes serious health concerns over the long term. Several phytocompounds have emerged as promising sources of anti-inflammatory agents. is a traditional medicine for inflammatory and toxicity insults; however, this has not been scientifically confirmed.

View Article and Find Full Text PDF

Plant-derived essential oils (EO) offer a natural alternative to chemical pesticides for eco-friendly pest control approaches. Aceria pongamiae Keifer, a notorious pest that affects Pongamia pinnata (L.) Pierre has mainly been controlled using synthetic acaricides leading to resistance development and environmental issues.

View Article and Find Full Text PDF

Natural bioactive compounds encompass a vast array of molecules derived from plants, fungi, marine organisms, and other natural sources [...

View Article and Find Full Text PDF
Article Synopsis
  • Citrus peels, often discarded and seen as waste, were studied for their potential pharmacological benefits, focusing on the essential oil extracted from them.
  • The essential oil from Citrus reticulata Blanco (CREO) showed significant antioxidant, antibacterial, and anticancer properties through various tests, indicating its health benefits.
  • Key compounds found in CREO, such as S-limonene and α-pinene, are likely responsible for its effectiveness against pathogens and in reducing breast cancer cell viability.
View Article and Find Full Text PDF

Objective: Doxorubicin (DOX) is a frontline antineoplastic drug that kills cancer cells through genotoxic mechanism; however, it induces organ toxicities. This study assayed whether morin hydrate (MOH) could abrogate DOX hepatorenal toxicity in rats.

Materials And Methods: There were 4 groups of rats: Control, MOH, DOX and MOH + DOX.

View Article and Find Full Text PDF

Ethnomedicinal plants are important sources of drug candidates, and many of these plants, especially in the Western Ghats, are underexplored. , a genus within the Fabaceae family, thrives in the biodiversity of the Western Ghats, Kerala, India, and holds significant ethnobotanical importance. However, many species remain understudied in terms of their biological efficacy, while some lack scientific validation for their traditional uses.

View Article and Find Full Text PDF

Plant secondary metabolites are important sources of biologically active compounds with wide pharmacological potentials. Among the different classes, the chalcones form integral pharmacologically active agents. Natural chalcones and bis-chalcones exhibit high antioxidant and anti-inflammatory properties in various experiments.

View Article and Find Full Text PDF
Article Synopsis
  • - The species in question are part of the Lauraceae family, widely used for spices and noted for their cosmetic and medicinal benefits.
  • - A study of the essential oil from (Burm. f.) J. Presl revealed it contains significant amounts of linalool and caryophyllene, along with other compounds like benzyl benzoate and eugenol.
  • - The essential oil demonstrated strong antioxidant activity and showed potential for inhibiting enzymes related to diabetes, as well as exhibiting antibacterial properties against various bacteria.
View Article and Find Full Text PDF

is a traditionally used plant in Ayurvedic and folk medicines. The plant is useful for the management of gastrointestinal diseases as well as skin diseases. In the present study, we analyzed the antitumor potential of in Dalton's lymphoma ascites tumor cells (DLA) and Ehrlich ascites carcinoma (EAC)-induced solid and ascites tumors.

View Article and Find Full Text PDF

Citrus plants are widely utilized for edible purposes and medicinal utility throughout the world. However, because of the higher abundance of the antimicrobial compound D-Limonene, the peel waste cannot be disposed of by biogas production. Therefore, after the extraction of D-Limonene from the peel wastes, it can be easily disposed of.

View Article and Find Full Text PDF

Plants are known to have numerous phytochemicals and other secondary metabolites with numerous pharmacological and biological properties. Among the various compounds, polyphenols, flavonoids, anthocyanins, alkaloids, and terpenoids are the predominant ones that have been explored for their biological potential. Among these, chalcones and bis-chalcones are less explored for their biological potential under in vitro experiments, cell culture models, and animal studies.

View Article and Find Full Text PDF

species are widely used as a food additive and also in various medicinal purposes. The plant is a rich source of essential oil and is predominantly extracted from the rhizomes. On the other hand, the leaves of the plants are usually considered as an agrowaste.

View Article and Find Full Text PDF

Plants have been employed in therapeutic applications against various infectious and chronic diseases from ancient times. Various traditional medicines and folk systems have utilized numerous plants and plant products, which act as sources of drug candidates for modern medicine. Artemisia is a genus of the Asteraceae family with more than 500 species; however, many of these species are less explored for their biological efficacy, and several others are lacking scientific explanations for their uses.

View Article and Find Full Text PDF

Spirulina is a kind of blue-green algae (BGA) that is multicellular, filamentous, and prokaryotic. It is also known as a cyanobacterium. It is classified within the phylum known as blue-green algae.

View Article and Find Full Text PDF

Background: Gastrointestinal cancer are the major form of cancer in developing countries, which comprises gastric cancer (GC), hepatic cancer (HCC), colorectal cancers (CRC), etc.; they account for a large number of cancer-related deaths globally. Gastrointestinal cancers generally have a multifactorial origin, where both genetic and dietary factors play prominent roles.

View Article and Find Full Text PDF

The wastes generated during the post-harvest handling of various agricultural commodities is rather under-utlilized. The peels of citrus fruits are often discarded as waste. Citrus peels are rich in essential oils and exhibit toxicity towards various insect species.

View Article and Find Full Text PDF

Infectious diseases and their vectors have remained a concern for human population from their historical origin. Microbial pathogens have also emerged as a potent threat to the healthcare systems even in developed countries. Essential oils remain a less explored method for infectious disease control; besides, the ultrasound-assisted extraction (UAE) of essential oil production has emerged as promising source of bioactive volatiles over conventional methods.

View Article and Find Full Text PDF

The Indian sarsaparilla () is a commonly used plant in Indian traditional medicine of Ayurveda for the preparation of various non-alcoholic beverages. However, limited studies are available on the essential oil of roots (HRO); therefore, the study evaluated the antioxidant, anti-inflammatory and antidiabetic activities of root essential oil as well as insecticide potential against the common pests of stored food materials (, and ). The repellant efficacy of HRO was found to be high against (8.

View Article and Find Full Text PDF

Background: Fruits are an important dietary component, which supply vitamins, minerals, as well as dietary fiber. In addition, they are rich sources of various biological and pharmacologically active compounds. Among these, temperate fruits are well studied for their pharmacological potentials, whereas tropical/subtropical fruits are less explored for their health impacts.

View Article and Find Full Text PDF

Essential oils are biologically and environmentally safe pesticidal compounds yielded from aromatic plants. Spices are important sources of essential oils, and they are widely used in the medicine, food, and various other industries. Among the different spices, Allspice () is underexplored in terms of its biological efficacy and a limited number of studies are available on the chemical composition of Allspice essential oil (AEO); thus, the present study evaluated the larvicidal property, the repellency, and the fumigant toxicity against common pests of stored products of AEO.

View Article and Find Full Text PDF
Article Synopsis
  • A traditional medicinal plant from the Salvadoraceae family is commonly used in folk medicine for treating rheumatism and inflammatory disorders.
  • The study found that its methanol extract has high levels of beneficial compounds like polyphenols and flavonoids, which give it strong antioxidant and anti-inflammatory properties.
  • The extract also showed significant cytotoxic effects on breast cancer cells, suggesting it could potentially be used in cancer treatment due to its ability to induce cell death.
View Article and Find Full Text PDF

is widely used in traditional medicines, and the different parts of the plant, such as bark, leaves, and flowers, are used for essential oil production. The present study compared the chemical composition of the essential oil of extracted from the leaves and flowers. In addition, efficacy of these essential oils against the two common pests and was also evaluated.

View Article and Find Full Text PDF