Simple Vision Function Tests that Distinguish Eyes with Early to Intermediate Age-related Macular Degeneration.

Purpose: To present and compare baseline vision findings in eyes with early age-related macular degeneration (E-AMD), intermediate AMD (I-AMD), and age-similar participants with normal aging changes to the retina (No-AMD).

Methods: Two hundred and thirty-seven eyes of 125 individuals (66.4% female, mean age 75.

FINGERPRINT SIGN OF THE HENLE FIBER LAYER.

Purpose: To describe the appearance of concentric, fingerprint-like waves within the Henle fiber layer (HFL) using en face optical coherence tomography in patients with tractional pathologies of the retina.

Methods: Retrospective analysis of six eyes of six patients imaged by optical coherence tomography with volumetric slabs positioned at the level of the HFL.

Results: Optical coherence tomography data from six patients with tractional vitreoretinal pathology were reviewed.

RETINAL DYSTROPHY IN A PATIENT WITH McARDLE DISEASE.

Purpose: To report a case of pattern dystrophy in a patient with McArdle disease, a rare autosomal recessive disorder of glycogen metabolism.

Methods: Case report.

Results: A 29-year-old woman with a history of muscle biopsy-confirmed McArdle disease presented with fundus findings consistent with pattern dystrophy.

AUTOSOMAL RECESSIVE BESTROPHINOPATHY: MULTIMODAL IMAGING UPDATE.

Background: Autosomal recessive bestrophinopathy is part of the diverse spectrum of retinal diseases caused by mutations in the BEST1 gene.

Methods: A case report.

Results: We present a case that highlights the classic retinal findings of autosomal recessive bestrophinopathy with an emphasis on modern multimodal imaging.

Neovascularization of the iris in retinoschisis.

Purpose: To report the association of rubeosis iridis with chronic bullous degenerative peripheral retinoschisis.

Observations: A 63-year-old female presented with acute hyphema and neovascularization of the iris in association with elevated intraocular pressure. Posterior segment examination including imaging revealed no vascular occlusion as a potential cause.

ACUTE MACULAR NEURORETINOPATHY WITHOUT NEAR-INFRARED REFLECTANCE-AN ATYPICAL CASE PRESENTATION.

Background: Acute macular neuroretinopathy is a rare disease that with the help of multimodal imaging is being diagnosed more frequently.

Methods: An atypical case is presented and followed by multimodal imaging.

Results: A typical acute macular neuroretinopathy lesion was seen on biomicroscopic examination and spectral domain optical coherence tomography examination.

Paraneoplastic vitelliform retinopathy in a patient with treated choroidal melanoma.

Purpose: To describe a peculiar case of paraneoplastic vitelliform maculopathy/retinopathy in a patient with treated choroidal melanoma.

Methods: A case report of a 58-year-old woman with a history of treated choroidal melanoma 16 years before developing visual changes in the setting of metastatic choroidal melanoma.

Results: We demonstrate bilateral, multifocal vitelliform subretinal lesions and focal, neurosensory retinal detachment associated with metastatic melanoma.

Chronic exogenous exophiala dermatitidis endophthalmitis.

Purpose: To describe a case of chronic exogenous Exophiala dermatitidis endophthalmitis.

Methods: Retrospective chart review and case report.

Results: A 60-year-old man with history of chronic herpes zoster keratitis complicated by secondary fungal keratitis treated with penetrating keratoplasty presented with a white cataract, chronic anterior uveitis, and counting fingers vision in the left eye.

Acute retinal necrosis secondary to multidrug-resistant herpes simplex virus 2 in an immunocompetent adolescent.

Purpose: To report the clinical course of a patient with acute retinal necrosis resulting from a multidrug-resistant strain of herpes simplex virus 2.

Methods: Observational case report.

Results: A 17-year-old man with no identifiable immune deficiency presented with pain and decreased vision in his left eye.

Central serous chorioretinopathy after trabeculectomy in a patient with microphthalmos and congenital rubella syndrome.

Purpose: To describe a case of central serous chorioretinopathy after trabeculectomy surgery in an eye with microphthalmos in the setting of congenital rubella syndrome.

Methods: A Case report with color fundus photographs, fluorescein angiography, and spectral domain optical coherence tomography.

Results: A 46-year-old African American man, with a history of congenital heart disease and bilateral hearing loss, developed persistent vision loss in the left eye after trabeculectomy surgery.

Spectral domain optical coherence tomography findings in eyes with acute ischaemic retinal whitening.

Acute retinal ischaemia presents in various forms depending on the type and location of the associated vascular occlusion. Cotton wool spots have been considered one manifestation of ischaemia and represent swelling in the nerve fibre layer. However, clinical retinal whitening also occurs in areas not affected by cotton wool spots, and has distinguishing spectral domain optical coherence tomography (SD-OCT) features.

Rhegmatogenous Retinal Detachment in Patients with Acute Syphilitic Panuveitis.

Purpose: To describe the clinical characteristics and surgical management of rhegmatogenous retinal detachment (RD) in patients with acute syphilitic panuveitis.

Methods: Retrospective case series and comprehensive literature review.

Results: Including present and previously reported cases, we identified 11 eyes in 8 patients with acute syphilitic panuveitis that developed a rhegmatogenous RD.

En face spectral domain optical coherence tomography analysis of lamellar macular holes.

Purpose: To analyze the anatomical characteristics of lamellar macular holes using cross-sectional and en face spectral domain optical coherence tomography.

Methods: Forty-two lamellar macular holes were retrospectively identified for analysis. The location, cross-sectional length, and area of lamellar holes were measured using B-scans and en face imaging.

Sensitivity of fluid detection in patients with neovascular amd using spectral domain optical coherence tomography high-definition line scans.

Purpose: To determine the sensitivity of the Cirrus high-definition (HD) 5-line raster scans for detecting retinal fluid in neovascular age-related macular degeneration when using the spectral domain optical coherence tomography macular cubes as a gold standard.

Methods: Patients were retrospectively identified from their initial follow-up visit after being newly diagnosed with neovascular age-related macular degeneration in at least one eye. Patients were imaged with Cirrus spectral domain optical coherence tomography using the 512 × 128 macular cube scan and HD 5-line raster scan settings.

Intravitreous ranibizumab for persistent macular edema in retinal vein occlusion unresponsive to bevacizumab.

Purpose: To report successful treatment of persistent retinal edema associated with retinal vascular occlusion with ranibizumab after initial failure with bevacizumab intravitreal injections.

Methods: A retrospective chart review of all patients undergoing treatment with intravitreal bevacizumab for retinal vascular occlusion was undertaken. Clinical features of patients who were switched to monthly ranibizumab because of persistent and/or worsening retinal edema despite multiple (six or more) monthly intravitreal bevacizumab injections were selected for review.

Autofluorescence and spectral domain OCT findings in Alport syndrome.

Purpose: The purpose of this study was to report novel autofluorescence and spectral domain optic coherence tomography findings in a case of Alport syndrome.

Methods: Case report and literature review.

Results: A 30-year-old woman with a history of Alport syndrome presented with a full-thickness macular hole in her right eye and evidence of vitreofoveal traction in her asymptomatic left eye.

Continued vision loss from progressive expansion of inactive chorioretinal scars in a myopic patient with well-controlled sympathetic ophthalmia.

Purpose: To describe significant vision loss caused by enlargement of chorioretinal scars related to sympathetic ophthalmia despite adequate control of intraocular inflammation.

Methods: A case report of a 62-year-old man who developed sympathetic ophthalmia after a vitrectomy, which was successful in repairing a rhegmatogenous retinal detachment.

Results: Progressive expansion of chorioretinal scars occurred despite successful control of intraocular inflammation related to sympathetic ophthalmia.

Retinal pigment epitheliopathy, macular telangiectasis, and intraretinal crystal deposits in HIV-positive patients receiving ritonavir.

Purpose: The purpose of this study was to describe the occurrence of a retinal pigment epitheliopathy associated with macular telangiectasis and intraretinal crystal deposits in three human immunodeficiency virus-positive patients receiving long-term ritonavir as part of highly active antiretroviral therapy.

Methods: The patient's records were reviewed.

Results: The CD4 T-cell counts at presentation were 163 cells per microliter, 464 cells per microliter, and 349 cells per microliter, and viral loads were undetectable in all patients.

Macular fibrosis in Coats disease.

Purpose: The purpose of this study was to describe the angiographic features and visual impact of macular fibrosis in patients with Coats disease.

Methods: This is a single institution retrospective case series. Charts of patients diagnosed with Coats disease between 1973 and 2007 were reviewed.

Resolution of a giant pigment epithelial detachment after treatment with intravitreal bevacizumab.

Purpose: To describe a patient with a giant pigment epithelial detachment (PED) successfully treated with intravitreal bevacizumab.

Design: Retrospective, observational case report.

Methods: The patient's records were reviewed.