Preprocedural frailty status and short- and long-term mortality risk after endovascular therapy in elderly acute ischemic stroke patients.

Objectives: To evaluate the Laboratory-based Frailty Index (FI-LAB) for predicting mortality following endovascular therapy (EVT) in elderly patients with large vessel occlusion acute ischemic stroke (LVO-AIS).

Methods: This retrospective study enrolled 382 patients aged ≥60 years undergoing EVT. FI-LAB was constructed using 44 preprocedural laboratory parameters.

Day 3 neutrophil-to-lymphocyte ratio and its derived indices predict 90-day poor outcomes following mechanical thrombectomy in acute ischemic stroke patients.

Objective: To investigate the dynamic changes in neutrophil-to-lymphocyte ratio (NLR) and its derived indices following mechanical thrombectomy (MT) in patients with acute ischemic stroke (AIS) and evaluate their predictive value for prognosis.

Methods: This single-center retrospective cohort study included AIS patients who underwent MT at Zhongshan Hospital of Xiamen University from January 2018 to February 2024. Peripheral blood samples were collected on admission, day 1, and day 3 after MT to determine the NLR, derived NLR (dNLR), and neutrophil-monocyte-to-lymphocyte ratio (NMLR).