Neuropsychological test validation of speech markers of cognitive impairment in the Framingham Cognitive Aging Cohort.

Aim: Although clinicians primarily diagnose dementia based on a combination of metrics such as medical history and formal neuropsychological tests, recent work using linguistic analysis of narrative speech to identify dementia has shown promising results. We aim to build upon research by Thomas JA & Burkardt HA et al. (J Alzheimers Dis.

Social media use while listening to new material negatively affects short-term memory in college students.

Increased access to electronic devices and the ubiquity of social media has resulted in a rapid rise in the prevalence of students "multitasking" while in a classroom setting. While some data indicate the use of electronic devices in class can improve the classroom environment, other studies demonstrate the opposite finding. Moreover, it remains unclear if using social networking sites such as Instagram impacts performance on cognitive tasks when students are presented new material and, if so, what features of Instagram modulate this response.

Assessing the Utility of Language and Voice Biomarkers to Predict Cognitive Impairment in the Framingham Heart Study Cognitive Aging Cohort Data.

Background: There is a need for fast, accessible, low-cost, and accurate diagnostic methods for early detection of cognitive decline. Dementia diagnoses are usually made years after symptom onset, missing a window of opportunity for early intervention.

Objective: To evaluate the use of recorded voice features as proxies for cognitive function by using neuropsychological test measures and existing dementia diagnoses.

Cellular organization of normal mouse liver: a histological, quantitative immunocytochemical, and fine structural analysis.

The cellular organization of normal mouse liver was studied using light and electron microscopy and quantitative immunocytochemical techniques. The general histological organization of the mouse liver is similar to livers of other mammalian species, with a lobular organization based on the distributions of portal areas and central venules. The parenchymal hepatocytes were detected with immunocytochemical techniques to recognize albumin or biotin containing cells.

Comparison of germanium oxide fibers with silica and sapphire fiber tips for transmission of erbium: YAG laser radiation.

Background And Objectives: Endoscopic applications of the Erbium:YAG laser have been limited due to the lack of a suitable optical fiber delivery system. The purpose of this study was to compare the transmission of Er:YAG laser radiation through germanium oxide trunk fibers with silica and sapphire fiber tips for potential use in contact tissue ablation during endoscopy.

Study Design/materials And Methods: Er:YAG laser radiation with a wavelength of 2.

Side-firing germanium oxide optical fibers for use with erbium:YAG laser.

Background And Purpose: During recent experimental studies, the erbium:YAG laser has been shown to be more efficient for lithotripsy and more precise for incision of soft urinary tissues than the conventional holmium:YAG laser. Mid-infrared optical fibers are being developed to allow endoscopic delivery of Er:YAG laser radiation. This paper describes the simple construction and characterization of a side-firing germanium oxide fiber for potential use with the Er:YAG laser in endourology.