Bjerkandera adusta TM11 for the bioremediation of fluoroquinolone antibiotics spiked in wastewater: A sustainable approach to pharmaceutical contaminant biotransformation.

Global antibiotic consumption is increasing dramatically. Antibiotic release into the environment, primarily through wastewater discharge, has serious impacts for human and animal health and microbial ecosystems. To address this issue, white-rot fungi present a promising solution, as they possess oxidative enzymes that can degrade these pollutants.

Responses to and detoxification of esculin in white-rot fungi.

Plant metabolites have a great potential for limiting the spread of harmful fungi. However, a better understanding of the mode-of-action of these molecules and the defense systems developed by fungi to resist them, is needed to assess the benefits/risks of using them as antifungal treatment. White-rot fungi are excellent models in this respect, as they have adapted to the hostile habitat that is wood.

Valorizing fungal diversity for the degradation of fluoroquinolones.

Continued widespread use of antibiotics, especially fluoroquinolones, raises environmental concerns, as its driving bacterial resistance and disrupts microbial ecosystems. Here we investigate the biodegradation of ten fluoroquinolone antibiotics (six for medical use and four for veterinary use) by ligninolytic fungi, including , , , , , , , , and . The results show significant variations between strains in the efficiency of antibiotic transformation.

A New Phenolic Acid Decarboxylase from the Brown-Rot Fungus Natively Decarboxylates Biosourced Sinapic Acid into Canolol, a Bioactive Phenolic Compound.

Rapeseed meal (RSM) is a cheap, abundant and renewable feedstock, whose biorefinery is a current challenge for the sustainability of the oilseed sector. RSM is rich in sinapic acid (SA), a -hydroxycinnamic acid that can be decarboxylated into canolol (2,6-dimethoxy-4-vinylphenol), a valuable bioactive compound. Microbial phenolic acid decarboxylases (PADs), mainly described for the non-oxidative decarboxylation of ferulic and -coumaric acids, remain very poorly documented to date, for SA decarboxylation.

Insights into exo- and endoglucanase activities of family 6 glycoside hydrolases from Podospora anserina.

The ascomycete Podospora anserina is a coprophilous fungus that grows at late stages on droppings of herbivores. Its genome encodes a large diversity of carbohydrate-active enzymes. Among them, four genes encode glycoside hydrolases from family 6 (GH6), the members of which comprise putative endoglucanases and exoglucanases, some of them exerting important functions for biomass degradation in fungi.