Publications by authors named "Anne Requirand"

Background: To assess the feasibility, acceptability, safety, and short-term benefits of a tailored cardiac rehabilitation program for children and adolescents with long QT syndrome (LQTS).

Methods: Eight participants, aged between 6 and 18, with a positive LQTS genotype and impaired cardiorespiratory fitness, were enrolled in a 12-week centre-based cardiac rehabilitation program. The program included supervised exercise training group sessions (aerobic, resistance, and outdoor activities) and patient education workshops.

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  • A study on the TRANSITION-CHD program aimed to support adolescents and young adults with congenital heart disease (CHD) in transitioning to adult healthcare, focusing on improving their health-related quality of life (HRQoL).
  • The trial involved 200 participants aged 13-25, comparing those in the transition program with a standard care group, evaluating changes in HRQoL, disease knowledge, and mental and physical health.
  • Results showed the transition group had significantly better HRQoL, disease knowledge, and psychosocial health compared to the control group, indicating the program's effectiveness and potential for broader implementation in healthcare for young people with CHD.
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Background: Aerobic fitness is a predictor of cardiovascular health which correlates with health-related quality of life in the general population. The aim is to evaluate the aerobic capacity by cardiopulmonary exercise test (CPET) in children with sickle cell disease in comparison with healthy matched controls.

Methods: Controlled cross-sectional study.

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Background: The evaluation of health status by cardiopulmonary exercise test (CPET) has shown increasing interest in the paediatric population. Our group recently established reference Z-score values for paediatric cycle ergometer VO, applicable to normal and extreme weights, from a cohort of 1141 healthy children. There are currently no validated reference values for the other CPET parameters in the paediatric population.

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Aims: Overweight and obesity in children with congenital heart disease (CHD) represent an alarming cardiovascular risk. Promotion of physical activity and cardiac rehabilitation in this population requires assessing the level of aerobic fitness (VO2max) by a cardiopulmonary exercise test (CPET). Nevertheless, the interpretation of CPET in overweight/obese children with CHD remains challenging as VO2max is affected by both the cardiac condition and the body mass index (BMI).

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  • * Researchers assessed VO2max in a large sample of 909 French children and validated the findings with an additional 232 children from Germany and the US, using advanced mathematical models.
  • * The new logarithmic Z-score model proved to be more accurate than previous methods and is suitable for children of all weights, enhancing the ability to assess aerobic fitness in young patients.
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Background: In children with congenital long QT syndrome (LQTS), the risk of arrhythmic events during exercise commonly makes it difficult to balance exercise restrictions promotion of physical activity. Nevertheless, in children with LQTS, cardiorespiratory fitness, muscle fitness, and physical activity, have been scarcely explored.

Materials And Methods: In this prospective, controlled, cross-sectional study, 20 children with LQTS (12.

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Purpose: Childhood cancer survivors are at increased risk for cardiovascular disease. Maximal oxygen uptake (VO) is a major determinant of cardiovascular morbidity. The aim of this study was to compare aerobic capacity, measured by cardiopulmonary exercise test (CPET), of adolescents and young adults in remission with that of healthy controls and to identify the predictors of aerobic capacity in this population.

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Objectives: To evaluate, with a cardiopulmonary exercise test (CPET), the cardiopulmonary fitness of children with asthma, in comparison to healthy controls, and to identify the clinical and CPET parameters associated with the maximum oxygen uptake (VO) in childhood asthma.

Design: This cross-sectional controlled study was carried out in CPET laboratories from two tertiary care paediatric centres. The predictors of VO were determined using a multivariable analysis.

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Background: To evaluate the change in aerobic fitness (VO), measured by cardio-pulmonary exercise test (CPET), in children with congenital heart disease (CHD), compared to matched healthy controls, and identify predictors of VO change with time in this specific population.

Method: This longitudinal retrospective multicentre cohort study was carried out from 2010 to 2020. We included CHD paediatric patients from the cohort of a previous cross-sectional study, who had a second CPET at least 1 year after the first one, during their follow-up.

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Background: Because of sports and exercise restrictions, children with inherited cardiac disease are at risk of physical deconditioning. Guidelines on sports participation in cardiovascular disease have become less restrictive over time, but their real-life application and behavioural impact have seldom been evaluated in children.

Aims: We aimed to evaluate adherence to the 2020 European Society of Cardiology guidelines on sports and exercise in children with inherited cardiac arrhythmia and inherited cardiomyopathy; we also sought to evaluate their aerobic fitness, and the behavioural impact of inherited cardiac diseases on physical activity in children.

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Article Synopsis
  • Advances in pediatric cardiology have enhanced survival rates for children with inherited cardiac disorders, but there's limited research on how these conditions affect their quality of life (QoL) and physical activity.
  • The QUALIMYORYTHM trial is a multicenter study aimed at comparing the QoL of children aged 6 to 17 with inherited cardiac arrhythmias or cardiomyopathies to that of healthy peers and examining various factors influencing their QoL.
  • Results from this trial seek to provide stronger evidence for guidelines regarding sports participation for young athletes with inherited cardiac disorders, moving beyond reliance on expert opinions.
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Objective: To assess the inspiratory demand in young infants with acute viral bronchiolitis to provide a physiological basis for initial flow setting for patients supported with high flow nasal cannula.

Study Design: Prospective study in 44 infants up to 6 months old with acute viral bronchiolitis, admitted to a pediatric intensive care unit from November 2017 to March 2019. Airflow measurements were performed using spirometry.

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Background: Recent advances in the field of congenital heart disease (CHD) have significantly improved the overall prognosis. Now more attention is being given to health-related quality of life (HRQoL) and promotion of physical activity. Non-invasive relaxation therapy may be effective in cardiac patients concerned with exercise-induced dyspnoea.

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