Publications by authors named "Anna Lucas Calduch"
Article Synopsis
- This study evaluated the outcomes of 44 patients with recurrent glioblastoma who underwent reirradiation after an initial treatment, finding that median overall survival after the second treatment was 14.9 months.
- The most common reirradiation method used was 35 Gy in 10 fractions, with mild acute side effects and a 40% rate of radiological response; however, many patients also experienced early distant progressions.
- Factors like a Karnofsky index below 70 and smaller recurrence sizes were linked to better overall survival, suggesting reirradiation is a viable option, especially for patients in good health with smaller lesions.
Purpose: Stereotactic body radiation therapy (SBRT) is a treatment modality with curative intent for oligometastatic cancer patients, commonly defined by a low-burden metastatic disease with 1-5 systemic metastases. Better knowledge of the clinical profile and prognostic factors in oligometastatic cancer patients could help to improve the selection of candidates who may obtain most benefits from SBRT. The objective of this study was to describe the clinical data and outcome in term of overall survival (OS) of patients with oligometastatic disease treated with SBRT over a 6-year period.
View Article and Find Full Text PDFEvaluation of the Hippocampal Normal Tissue Complication Model in a Prospective Cohort of Low Grade Glioma Patients-An Analysis Within the EORTC 22033 Clinical Trial.
Front Oncol
October 2019
To evaluate the performance of the hippocampal normal tissue complication model that relates dose to the bilateral hippocampus to memory impairment at 18 months post-treatment in a population of low-grade glioma (LGG) patients. LGG patients treated within the radiotherapy-only arm of the EORTC 22033-26033 trial were analyzed. Hippocampal dose parameters were calculated from the original radiotherapy plans.
View Article and Find Full Text PDFACUTE RADIATION SYNDROME OR ACUTE RADIATION SICKNESS IS CLASSICALLY SUBDIVIDED INTO THREE SUBSYNDROMES: the hematopoietic, gastrointestinal and neurovascular syndrome but many other tissues can be damaged. The time course and severity of clinical signs and symptoms are a function of the overall body volume irradiated, the inhomogeneity of dose exposure, the particle type, the absorbed dose and the dose rate. Classical pathophysiology explain the failure of each of these organs and the timing of appearance of their signs and symptoms due to radiation-induced cytocidal effects of a great number of parenchymal cells of hierarchically organized tissues.
View Article and Find Full Text PDFPrimary mucosa-associated lymphoid tissue lymphoma of the salivary glands: a multicenter Rare Cancer Network study.
Int J Radiat Oncol Biol Phys
January 2012
Purpose: Involvement of salivary glands with mucosa-associated lymphoid tissue (MALT) lymphoma is rare. This retrospective study was performed to assess the clinical profile, treatment outcome, and prognostic factors of MALT lymphoma of the salivary glands.
Methods And Materials: Thirteen member centers of the Rare Cancer Network from 10 countries participated, providing data on 63 patients.