Publications by authors named "Ankur Pandey"

Background: Identifying severe aortic stenosis can be difficult especially among patients with low-flow states compared to normal flow. Non-invasive modalities can aid in the diagnosis for timely treatment.

Methods: In this retrospective, single-center study of patients with aortic stenosis who underwent transcatheter aortic valve replacement (TAVR), we calculated stroke volume using CT blood pool based (CT-blp) analysis, echocardiogram and right heart catheterization (cath) performed before TAVR.

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  • - Peritoneal malignancies are tumors that arise from the peritoneum, including both primary tumors (like mesothelioma) and secondary tumors that spread from other cancer sites, such as the gastrointestinal tract or gynecological areas.
  • - The treatment approach is shifting from traditional palliative care to a multimodal strategy that combines cytoreductive surgery with hyperthermic intraperitoneal chemotherapy, which has led to improved survival rates.
  • - Imaging plays a critical role in diagnosing and managing these malignancies, using methods like CT, MRI, and PET to help in staging, monitoring therapy response, and selecting appropriate patients based on tumor burden and treatment outcomes.
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Pancreas transplantation is a complex surgical procedure performed to restore normoglycemia in patients with type 1 diabetes and includes whole/segmental organ transplant and islet cell transplantation (ICT). In the United States, simultaneous pancreas-kidney transplant (SPK) is most commonly performed due to the higher occurrence of end-stage renal disease in diabetic patients. Understanding the surgical technique and postoperative anatomy is imperative for effective and accurate surveillance following transplantation.

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Neuroendocrine neoplasms (NENs) are rare neoplasms originating from neuroendocrine cells, with increasing incidence due to enhanced detection methods. These tumors display considerable heterogeneity, necessitating diverse management strategies based on factors like organ of origin and tumor size. This article provides a comprehensive overview of therapeutic approaches for NENs, emphasizing the role of imaging in treatment decisions.

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Cosmeceuticals have gained great importance and are among the top-selling products used for skin care. Because of changing lifestyles, climate, and increasing pollution, cosmeceuticals are utilized by every individual, thereby making cosmeceuticals a fruitful field for research and the economy. Cosmeceuticals provide incredibly pleasing aesthetic results by fusing the qualities of both cosmetics and medicinal substances.

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  • * Recent FDA approval of Risdiplam has shifted perceptions about RNA's role in medicine, highlighting its regulatory functions and involvement in various diseases.
  • * Understanding RNA's complex structures and potential for small-molecule interactions can enhance therapeutic options and accelerate the drug discovery process.
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  • - The study focuses on improving prognostic models for unresectable intrahepatic cholangiocarcinoma (ICCA) by incorporating baseline volumetric multiparametric MRI data, as current models, like the Fudan score, lack imaging insights that reflect tumor biology.
  • - Researchers analyzed data from 114 patients treated with systemic chemotherapy and found that a high pre-treatment ADC value was a strong indicator of overall survival, outperforming traditional imaging assessments used in the Fudan score.
  • - By integrating objective ADC measurements into the Fudan model, the modified ADC-Fudan model significantly enhanced survival predictions, showing better differentiation among risk groups and improving prognostic accuracy by 11%.
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Autoimmune lupus enteritis in systemic lupus erythematosus (SLE) is a rare manifestation that comprises of gastrointestinal tract inflammation with supportive images and/or biopsy findings. We report a unique case of widespread lupus enteritis occurring late in the disease process and in isolation without additional features of active SLE but in the presence of SLE serological activity. There was no clear evidence of active mesenteric vasculitis, intestinal pseudo-obstruction, protein-losing enteropathy, or coagulopathy by imaging or histopathology.

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  • Monkeypox virus (MPXV) presents a potential public health threat, mainly found in Africa, and while smallpox vaccines offer limited protection, there is a need for effective antiviral treatments.
  • The study identified seven novel small molecules (EH1-EH7) using computational methods, with EH4 showing the strongest binding to MPXV proteins, suggesting its potential as a treatment.
  • This research aims to develop new antiviral therapeutics for monkeypox and other related viruses, highlighting the importance of drug discovery in response to this emerging infection.
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In this work, we investigate the nanoparticle-cell wall interaction by NiO and mixed metal oxide CuO-NiO nanoparticles. We have synthesized and characterized the nanoparticles using XRD, FESEM, EDS, UV vis. spectroscopy, FTIR, Zeta, and TEM analysis in our previous work.

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Retroperitoneal abscesses are rare and life-threatening. The incidence of abscesses after open cholecystectomies is <1% disregarding location. 11 cases reporting post-cholecystectomy retroperitoneal abscesses were archived on PubMed, 7 associated with gallstone retaining or spillage.

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: To investigate radiomics ability in predicting hepatocellular carcinoma histological degree of differentiation by using volumetric MR imaging parameters. : Volumetric venous enhancement and apparent diffusion coefficient were calculated on baseline MRI of 171 lesions. Ninety-five radiomics features were extracted, then random forest classification identified the performance of the texture features in classifying tumor degree of differentiation based on their histopathological features.

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Micro phase separation in a thin film of a polymer blend leads to interesting patterns on different substrates. A plethora of studies in this field discussed the effect of the surface energy of the underlying tethered polymer brush or substrate on the final morphology of the polymer blend. The conventional process toward the final morphology is rather slow.

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The advent of COVID-19 pandemic has made it necessary to wear masks across populations. While the N95 mask offers great performance against airborne infections, its multilayered sealed design makes it difficult to breathe for a longer duration of use. The option of using highly breathable cloth or silk masks especially for a large populace is fraught with the danger of infection.

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Tuberculosis (TB) is a slow growing, potentially debilitating disease that has plagued humanity for centuries and has claimed numerous lives across the globe. Concerted efforts by researchers have culminated in the development of various strategies to combat this malady. This review aims to raise awareness of the rapidly increasing incidences of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis, highlighting the significant modifications that were introduced in the TB treatment regimen over the past decade.

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  • * By varying e-beam dosage, researchers observed that both PS and PMMA behave as negative-tone resists at higher doses, while chain scission of PMMA at the edges leads to confined dewetting effects.
  • * This method results in significantly smaller patterns compared to traditional techniques, and selectively removing PMMA blocks can further reduce feature sizes by an additional 50%.
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  • The study aimed to determine how many transarterial chemoembolization (TACE) sessions improve overall survival in patients with unresectable hepatocellular carcinoma (HCC) and identified different patient subgroups based on tumor characteristics.
  • Results showed that patients with ill-defined HCC had worse survival outcomes, but multiple TACE sessions (≥4) significantly improved their overall survival. In contrast, well-defined lesions did not benefit from additional TACE beyond the initial treatment.
  • Notably, ADC-nonresponders (those with less than 25% change in apparent diffusion coefficient) experienced significant survival benefits from sequential TACE, especially after 3 sessions, while ADC-responders did not see any survival
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Aim: To evaluate the association between single time-point quantitative liver and spleen volumes in patients with PSC and transplant-free survival, independent of Mayo risk score.

Materials And Methods: This HIPAA-compliant retrospective study included 165 PSC patients in a hospital. Total (T), and lobar (right [R], left [L], and caudate [C]) liver volumes and spleen volume (S) were measured.

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Purpose: To evaluate the use of volumetric multiparametric MRI in differentiating pancreatic intraductal papillary mucinous neoplasms (IPMNs) from serous cystadenomas (SCAs) METHODS: Included patients (123 patients with pancreatic cystic neoplasms (PCNs) measuring ≥ 10 mm) were stratified into two groups based on cyst type. Axial cyst size, region of interest (ROI)-based apparent diffusion coefficient (ADC) and volumetric data, including cyst volume, volumetric apparent diffusion coefficient (vADC), and volumetric venous enhancement (vVE) were extracted and compared between the two groups. Univariate and multiple logistic regression was used to develop models for distinguishing between IPMNs and SCAs.

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Objectives: We aimed to evaluate the independent predictive role of baseline imaging biomarkers for overall survival (OS) and transplant-free survival (TFS) in patients with HCC and assess the incremental value of these biomarkers to current staging systems.

Methods: In this retrospective IRB approved study, the clinical, laboratory, and imaging parameters of 304 HCC patients were collected. Cox regression model was utilized to identify the potential predictors of survival.

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  • The study aimed to assess how changes in the apparent diffusion coefficient (ADC) histogram after transarterial chemoembolization (TACE) could predict survival rates in patients with well-defined hepatocellular carcinoma (HCC).
  • Researchers analyzed data from 104 HCC patients who underwent TACE between 2005 and 2016, measuring various MRI metrics and utilizing statistical models to determine predictors of survival.
  • Results indicated that a significant change in ADC (ΔADC) and a decrease in ADC-kurtosis (ΔkADC) were linked to longer survival, with higher response rates (≥ 35% change in ADC) correlating to the best survival outcomes.
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  • This study aims to determine if changes in volumetric ADC (vADC) and volumetric venous enhancement (vVE) after transarterial chemoembolization (TACE) can predict the histological grading of hepatocellular carcinoma (HCC).
  • The research involved a retrospective analysis of 106 HCC patients, using MR imaging and comparing different tumor grades based on volumetric measurements taken before and after TACE. Results showed that low-grade tumors had more significant changes in vADC and vVE compared to high-grade tumors.
  • The study concludes that monitoring changes in vADC and vVE after TACE could help non-invasively assess the severity of HCC, especially when combined with the
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Objectives: We aimed to evaluate the role of volumetric ADC (vADC) and volumetric venous enhancement (vVE) in predicting the grade of tumor differentiation in hepatocellular carcinoma (HCC).

Methods: The study population included 136 HCC patients (188 lesions) who had baseline MR imaging and histopathological report. Measurements of vVE and vADC were performed on baseline MRI.

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Unfortunately the article was published with a spell error in the co-author names "Ankur Pandy and Pallavi Pandy". The correct co-author names should be Ankur Pandey and Pallavi Pandey".

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