Per- and poly-fluoroalkyl substances (PFAS) are accumulative, persistent and pervasive environmental contaminants known to cause adverse effects in wildlife after prolonged exposure. Oviparous species, particularly during their embryonic development stages, are highly susceptible to PFAS-related toxicity. Chronic exposure to these substances has been linked to bioaccumulation, resulting in arrested embryonic development, weakened immune responses, and reproductive defects in these animals.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
Purpose: Pergularia daemia Forsk. (Asclepiadaceae) is a traditionally reported medicinal herb used to treat joint pain and arthritis. However, there are no scientific reports about anti-arthritic activity of P.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
March 2015
Quantum dots not only act as nanocarrier but also act as stable and resistant natural fluorescent bio markers used in various in vitro and in vivo photolabelling and biological applications. In this study, the antimicrobial potential of TGA-CdTe QDs and commercial phenolics (rutin and caffeine) were investigated against Escherichiacoli. UV absorbance and fluorescence quenching study of TGA-CdTe QDs with rutin and caffeine complex was measured by spectroscopic technique.
View Article and Find Full Text PDFPyrene containing Schiff base molecule, namely 4-[(pyren-1-ylmethylene)amino]phenol (KB-1), was successfully synthesized and well characterized by using (1)H, (13)C NMR, FT-IR, and EI-MS spectrometry. UV-visible absorption, steady-state fluorescence, time-resolved fluorescence, and transient absorption spectroscopic techniques have been employed to elucidate the photophysical processes of KB-1. It has been demonstrated that the absorption characteristics of KB-1 have been bathochromatically tuned to the visible region by extending the π-conjugation.
View Article and Find Full Text PDFEpilepsy prevails to be a neurological disorder in anticipation of safer drugs with enhanced anticonvulsant efficacy as presently available drugs fails to offer adequate control of epileptic seizures in about one-third of patients. The objective of this study was to evaluate the effect of Trichosanthes tricuspidata methanolic extract (TTME) against epilepsy mediated oxidative stress in pilocarpine induced mice. Intraperitonial administration of pilocarpine (85 mg/kg) induced seizure in mice was assessed by behavior observations, which is significantly (p < 0.
View Article and Find Full Text PDFObjectives: The present work was carried out to investigate the free radical scavenging activity of the ethanol extract of C. halicacabum leaves (EECH), to study its antioxidant properties and anti-rheumatic effects in Wistar rats with CFA-induced arthritis, and to profile the phenolic components thereof by LC-MS/MS.
Methods: The free radical scavenging activities of the extract was evaluated by NO and superoxide anion scavenging assays.