The AM-4 Family of Layered Titanosilicates: Single-Crystal-to-Single-Crystal Transformation, Synthesis and Ionic Conductivity.

Flexible crystal() structures, which exhibit() single-crystal()-to-single-crystal() (SCSC) transformations(), are attracting attention() in many applied aspects: magnetic() switches, catalysis, ferroelectrics and sorption. Acid treatment() for titanosilicate material() AM-4 and natural() compounds with the same structures led to SCSC transformation() by loss() Na, Li and Zn cations with large structural() changes (20% of the unit()-cell() volume()). The conservation() of crystallinity through complex() transformation() is possible due() to the formation() of a strong hydrogen bonding() system().

Occurrence, Sources, and Health Risks of Polycyclic Aromatic Hydrocarbons in Road Environments from Harbin, a Megacity of China.

To obtain a comprehensive understanding about that occurrence, sources, and effects on human health of polycyclic aromatic hydrocarbons (PAHs) in road environmental samples from Harbin, concentrations of 32 PAHs in road dust, green belt soil, and parking lot dust samples were quantified. The total PAH concentrations ranged from 0.95 to 40.

Modeling historical budget for β-Hexachlorocyclohexane (HCH) in the Arctic Ocean: A contrast to α-HCH.

The historical annual loading to, removal from, and cumulative burden in the Arctic Ocean for β-hexachlorocyclohexane (β-HCH), an isomer comprising 5-12% of technical HCH, is investigated using a mass balance box model from 1945 to 2020. Over the 76 years, loading occurred predominantly through ocean currents and river inflow (83%) and only a small portion via atmospheric transport (16%). β-HCH started to accumulate in the Arctic Ocean in the late 1940s, reached a peak of 810 t in 1986, and decreased to 87 t in 2020, when its concentrations in the Arctic water and air were ∼30 ng m and ∼0.

Steady-State Based Model of Airborne Particle/Gas and Settled Dust/Gas Partitioning for Semivolatile Organic Compounds in the Indoor Environment.

Indoor semivolatile organic compounds (SVOCs), present in the air, airborne particles, settled dust, and other indoor surfaces, can enter the human body through several pathways. Knowing the partitioning between gaseous and particulate phases is important in identifying specific pathway contributions and thereby accurately assessing human exposure. Numerous studies have developed equilibrium equations to predict airborne particle/gas (P/G) partitioning in air () and dust/gas (D/G) partitioning in settled dust ().

Determination of 123 polycyclic aromatic hydrocarbons and their derivatives in atmospheric samples.

Polycyclic aromatic hydrocarbons (PAHs) are a class of toxic organic pollutants. Until now, they have been detected in many regions and various environmental matrix. However, not all PAHs are usually detected by researchers, and no methods is established to analyze systematically hundreds of PAHs.

In Situ Control of Thermal Activation Conditions by Color for Serpentines with a High Iron Content.

Serpentine heat treatment at temperatures of 650-750 °C yields magnesium-silicate reagent with high chemical activity. Precise and express control of roasting conditions in laboratory kilns and industrial aggregates is needed to derive thermally activated serpentines on a large scale. Color change in serpentines with a high iron content during roasting might be used to indicate the changes in chemical activity in the technological process.

Occurrence, removal and mass balance of substituted diphenylamine antioxidants in wastewater treatment plants in Northeast China.

Substituted diphenylamine antioxidants (SDPAs) are additives used in various commodities and are commonly found in environmental samples. However, limited information was available on their fate and removal in wastewater treatment plants (WWTPs). This paper reports the results on the occurrence and removal efficiency of ten selected SDPAs in six WWTPs equipped with different treatment processes in Northeast China.

Fate processes of Parabens, Triclocarban and Triclosan during wastewater treatment: assessment via field measurements and model simulations.

The high levels of parabens (including methyl-, ethyl- and propyl congeners), triclocarban (TCC) and triclosan (TCS) used every year in China might be a problem to the typical wastewater treatment plant (WWTP). This study addresses measurements of parabens, TCC and TCS Northern China WWTP and a modelling assessment on the occurrence, fate and removal pathways in WWTP. Per-capita emissions of the three parabens, TCC and TCS to the WWTP were estimated as 0.

Occurrence, Removal, and Mass Balance of Polycyclic Aromatic Hydrocarbons and Their Derivatives in Wastewater Treatment Plants in Northeast China.

Polycyclic aromatic hydrocarbons (PAHs), 33 methylated PAHs (Me-PAHs), and 14 nitrated PAHs (NPAHs) were measured in wastewater treatment plants (WWTPs) to study the removal efficiency of these compounds through the WWTPs, as well as their source appointment and potential risk in the effluent. The concentrations of ∑PAHs, ∑Me-PAHs, and ∑NPAHs were 2.01-8.

Treatment of particle/gas partitioning using level III fugacity models in a six-compartment system.

In this paper, two level III fugacity models are developed and applied using an environmental system containing six compartments, including air, aerosols, soil, water, suspended particulate matters (SPMs), and sediments, as a "unit world". The first model, assumes equilibrium between air and aerosols and between water and SPMs. These assumptions lead to a four-fugacity model.

Slopes and intercepts from log-log correlations of gas/particle quotient and octanol-air partition coefficient (vapor-pressure) for semi-volatile organic compounds: II. Theoretical predictions vs. monitoring.

The logarithm of gas/particle (G/P) partition quotient (logK) has been found to have a linear relationship with logK (octanol-air partition coefficient) with slope m and intercept b and logP (subcooled liquid vapor pressure) with slope m and intercept b. In the sister paper of the present work, analytical equations to predict the slope m and intercept b based on logK and predict the slope m and intercept b based on logP are developed using steady state theory. In this work, the equations are evaluated using world-wide monitoring data (262 pairs for m and b values and 292 pairs for m and b values produced from more than 10,000 monitiring data worldwide) for selected seven groups of semi-volatile organic compounds (SVOCs), including polybrominated diphenyl ethers (PBDEs), polychlorinated dibenzo-p-dioxins and polychorinated dibenzofurans (PCDD/Fs), polyclorinated biphenyl (PCBs), polycyclic aromatic hydrocarbons (PAHs), polychlorinated naphthalenes (PCNs), organochlorinated pesticides (OCPs), novel brominated flame retardants (NBFRs), and other selected halogenated flame retardants.

CHK1/2 Inhibitor Prexasertib Suppresses NOTCH Signaling and Enhances Cytotoxicity of Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma.

Platinum-based chemoradiotherapy is a mainstay of organ-preserving therapy for patients with head and neck squamous cell carcinoma cancer (HNSCC). However, the disease eventually becomes resistant to treatment necessitating new therapies. Checkpoint kinase 1 and 2 (CHK1/2) are serine/threonine kinases that activate cell-cycle checkpoints and serve a critical role in the DNA-damage response (DDR).

Modeling gas/particle partitioning of polybrominated diphenyl ethers (PBDEs) in the atmosphere: A review.

Gas/particle (G/P) partitioning of semi-volatile organic compounds (SVOCs) such as polybrominated diphenyl ethers (PBDEs), is an important atmospheric process due to its significance in governing atmospheric fate, wet/dry deposition, and long-range atmospheric transport. In this article, eight models published to predict the G/P partitioning of PBDEs are reviewed. These eight models are used to calculate the G/P partitioning quotient and particulate phase fraction of selected PBDE congeners.

Titanite-Containing Mineral Compositions and Their Chemical Treatment with Preparation of Functional Materials.

The waste of apatite-nepheline ore processing was chosen as the material of study for the present investigation. The chemical and phase compositions have been analyzed and the route of the new technology has been developed. Treatment of the waste with diluted hydrochloric acid enables to separate apatite, nepheline, titano-magnetite minerals from titanite (CaSiTiO).

Combined Targeting of Mutant p53 and Jumonji Family Histone Demethylase Augments Therapeutic Efficacy of Radiation in H3K27M DIPG.

Diffuse intrinsic pontine glioma (DIPG) is an aggressive pediatric brainstem tumor with a 5-year survival of <1%. Up to 80% of the DIPG tumors contain a specific K27M mutation in one of the two genes encoding histone H3 (H3K27M). Furthermore, p53 mutations found in >70-80% of H3K27M DIPG, and mutant p53 status is associated with a decreased response to radiation treatment and worse overall prognosis.

The Impact of DNA Repair Pathways in Cancer Biology and Therapy.

Genomic instability is one of the key hallmarks of cancer progression [1].[..

Dissimilar responses of larch stands in northern Siberia to increasing temperatures-a field and simulation based study.

Arctic and alpine treelines worldwide differ in their reactions to climate change. A northward advance of or densification within the treeline ecotone will likely influence climate-vegetation feedback mechanisms. In our study, which was conducted in the Taimyr Depression in the North Siberian Lowlands, w present a combined field- and model-based approach helping us to better understand the population processes involved in the responses of the whole treeline ecotone, spanning from closed forest to single-tree tundra, to climate warming.

Palliative Radiation Therapy for Symptomatic Control of Inoperable Renal Cell Carcinoma.

Renal cell carcinoma (RCC) is traditionally considered to be resistant to conventional low dose radiation therapy (RT). The emergence of image-guided stereotactic body radiation therapy (SBRT) made it possible to deliver much higher doses of radiation. Recent clinical trials of SBRT for RCC showed improvement in local control rates and acceptable toxicity.

Association between Hyperprolactinemia and Granulomatous Mastitis.

Granulomatous mastitis (GM) is a relatively uncommon inflammatory breast lesion with multiple suggested etiologies. Although most GM cases show association with lactation and pregnancy, a minority of cases have been linked to hyperprolactinemia caused by either dopamine antagonist medications or with intracranial lesions, such as pituitary adenoma. The goal of this study is to review the GM cases reported in the literature with a specific emphasis on those cases associated with hyperprolactinemia and prolactinomas and to identify cases of GM seen at the Cleveland Clinic Florida which demonstrate co-occurrences of GM and intracranial lesions.

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases.

Naturally occurring axonal pruning and neuronal cell death help to sculpt neuronal connections during development, but their mechanistic basis remains poorly understood. Here we report that beta-amyloid precursor protein (APP) and death receptor 6 (DR6, also known as TNFRSF21) activate a widespread caspase-dependent self-destruction program. DR6 is broadly expressed by developing neurons, and is required for normal cell body death and axonal pruning both in vivo and after trophic-factor deprivation in vitro.

DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1.

During nervous system development, spinal commissural axons project toward and across the ventral midline. They are guided in part by netrin-1, made by midline cells, which attracts the axons by activating the netrin receptor DCC. However, previous studies suggest that additional receptor components are required.