Three new quinones from (Fabaceae) and investigation of their bioactivity in BV-2 microglial cells.

Three new quinones were isolated from , identified as sennaquinone A (), quinquangulin-6--[α-L-rhamnopyranoside-(1→6)-β-D-glucopyranoside] () and rubrofusarin-6--[β-(6'-()-crotonylglucopyranoside] (), and nine other known compounds identified as quinquangulone () rubrofusarin-6--[-L-rhamnopyranoside-(1→6)-β-D-glucopyranoside] (), norrubrofusarin-6--β--glucopyranoside (cassiaside) (), rubrofusarin-6--β-D-glucopyranoside (), vanillic acid (), protocatechuic acid (), quercetin-3--sambubioside (), resveratrol (), and vomifoliol (). These compounds were determined by HR-ESI-MS, 1D and 2D NMR analyses and ECD calculation. The cytotoxicity of compounds , , and was first assessed in BV-2 microglial cell line by MTT assay.