Chorea Hyperglycemia Basal Ganglia (CHBG) Syndrome: A Case Report.

Chorea, characterized by sudden, involuntary movements of the face and limbs, arises from various causes, including neurodegenerative diseases, metabolic disorders, and structural brain changes, notably in the basal ganglia. Acute lesions in the basal ganglia due to ischemia or vascular pathology can also precipitate chorea. Hyperglycemia-induced basal ganglia changes, termed chorea hyperglycemia basal ganglia, predominantly affect elderly females with type 2 diabetes.

HIV-Associated Thrombotic Thrombocytopenic Purpura in a Virally Suppressed Patient With Normal CD4 Count: A Rare Presentation.

Thrombotic thrombocytopenic purpura (TTP) is a thrombotic process characterized by multiorgan failure secondary to microvascular thrombi comprising platelets and von Willebrand factor. HIV is a known risk factor for TTP. However, patients generally have low CD4+ count during initial presentation or subsequent flare-ups.

Drug-Induced Immune Thrombocytopenia From Administration of a Local Anesthetic Agent Resulting in Splenectomy.

Thrombocytopenia is a common clinical condition, and drug-induced immune thrombocytopenia (DITP) should be considered in hospitalized patients with severe thrombocytopenia who are exposed to new medications. The potential mechanism is described to be drug-triggered antibody-mediated platelet destruction causing petechiae and mucosal bleeding. Severe form of DITP can be refractory to systemic steroids and even intravenous immunoglobulin administration.

Positive acute viral infection markers, autoimmune disease and type II mixed cryoglobulinemia: a rare concurrence.

Cryoglobulins are abnormal serum immunoglobulins that tend to precipitate in intravascular compartments at temperatures lower than 37°C causing blood flow restriction to vital organs. They are divided into type I, II and III based on the immunoglobulin subtypes of the cryoprecipitates. Type II cryoglobulinemia is most commonly associated with viral infections, autoimmune diseases and lymphoproliferative disorders.