Publications by authors named "Amanda Liew"

The relationship between bats (order: Chiroptera) and humans is complex, highly contextualized across the globe, and dynamic. We assessed the United States (US) importation of live bats, as well as bat-derived products, from bat conservation and human health (zoonotic disease) perspectives. From 2015 to 2023, at least 284 bat species were imported into the US from at least 106 countries of origin, predominantly Indonesia.

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Rabbits can develop anemia due to serial phlebotomy or secondary to induced disease states. This study evaluated the effects of a single injection and three consecutive injections of erythropoietin in rabbits at 150 IU/kg and 1,000 IU/kg in order to determine whether these dosages produce a sustained increase in hematocrit. Analysis of CBC and chemistry parameters showed significant elevation in hematocrit one week after administration of 1,000 IU/kg erythropoietin for three consecutive days.

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  • The study investigates how alcohol and cannabis use patterns relate to PTSD and depression symptoms in civilians recently exposed to trauma, using data from 1618 participants over 12 weeks.
  • Three classes of substance use were identified: low, high, and increasing, with differences in PTSD and depression symptoms observed at baseline and throughout the study.
  • Results indicate that higher substance use correlates with more severe PTSD and depression symptoms, suggesting that understanding these patterns may help in timing treatment interventions.
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One of the common complications of non-traumatic subarachnoid hemorrhage (SAH) is delayed cerebral ischemia (DCI). Intrathecal (IT) administration of nicardipine, a calcium channel blocker (CCB), upon detection of large-artery cerebral vasospasm holds promise as a treatment that reduces the incidence of DCI. In this observational study, we prospectively employed a non-invasive optical modality called diffuse correlation spectroscopy (DCS) to quantify the acute microvascular cerebral blood flow (CBF) response to IT nicardipine (up to 90 min) in 20 patients with medium-high grade non-traumatic SAH.

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  • The study aimed to understand how SARS-CoV-2 affects companion animals in the US, focusing on clinical and epidemiologic aspects from March 2020 to December 2021.
  • Involved 204 pets (109 cats and 95 dogs) across 33 states with confirmed COVID-19 infections, primarily after being exposed to infected humans.
  • Findings showed that most infections were linked to human exposure, with significant illness duration (15 days for cats, 12 for dogs) and a 10-day gap between human and pet illness onset, highlighting the importance of tracking both species in disease transmission studies.
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Objectives: To evaluate the potential of contrast-enhanced spectral mammography (CESM) in reducing benign breast biopsy rate, thereby improving resource utilization. To explore its potential as a value-adding modality in the management of BI-RADS 4/5 lesions.

Materials And Methods: This was a prospective study conducted between July 2016 and September 2018.

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Article Synopsis
  • - SARS-CoV-2 has been found in various species, including pets like dogs and cats, with dog illnesses typically resolving on their own without extensive diagnosis.
  • - As new variants of SARS-CoV-2 arise, the symptoms and transmission dynamics in animals can change, prompting a need for ongoing monitoring.
  • - The report focuses on two dogs infected with the Delta variant, showing different symptoms despite similar exposure to a vaccinated human, underlining the necessity for more research on the impact of these variants on pets and other animals.
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Breast cancer metastasis to unusual locations may present as a diagnostic challenge. Recognizing the different manifestations of metastatic breast disease can help to guide patient treatment and assist in disease prognosis. The purpose of this article is to illustrate the imaging findings of some of the unusual or infrequent locations of breast metastases through a series of interesting cases and to revisit this uncommon clinical issue.

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  • The pandemic caused by the coronavirus has highlighted the impact of the Coronaviridae family on human disease outbreaks, particularly with SARS-CoV-2 emerging in late 2019.
  • Due to limited knowledge about SARS-CoV-2's characteristics, researchers are exploring data from other coronaviruses to better understand their risks and effects.
  • The study reviewed infections from various coronaviruses in different species and aims to promote a One Health approach that integrates human, animal, and environmental health for better preparedness and response to future outbreaks.
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BACKGROUND Pachydermodactyly, a benign and self-limiting cause of cutaneous fibromatosis, is an under-recognized condition. This little-known condition is important, as it mimics inflammatory arthropathy. CASE REPORT A 16-year-old male presented with a 2-year history of progressive, asymptomatic soft tissue swelling of the proximal interphalangeal joints (PIPJs) affecting the second to fourth fingers bilaterally.

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Previous work has shown that non-invasive optical measurement of low cerebral blood flow (CBF) is an acute biomarker of poor long-term cognitive outcome after repetitive mild traumatic brain injury (rmTBI). Herein, we explore the relationship between acute cerebral blood flow and underlying neuroinflammation. Specifically, because neuroinflammation is a driver of secondary injury after TBI, we hypothesized that both glial activation and inflammatory signaling are associated with acute CBF and, by extension, with long-term cognitive outcome after rmTBI.

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