Publications by authors named "Allison L Gradone"
Increased myositis and possible myocarditis in melanoma patients treated with immune checkpoint inhibitors in the COVID-19 era.
Cancer Immunol Immunother
October 2024
Article Synopsis
- A recent study investigated the rise in cases of immune checkpoint inhibitor (ICI)-mediated myocarditis and myositis among advanced melanoma patients at a single center between 2014 and 2021.
- The analysis showed that out of 366 patients treated from 2014 to 2019, there were no cases of myocarditis, whereas from 2019 to 2021, 10 out of 246 patients (4.1%) developed myocarditis, alongside 10 cases of myositis.
- The results indicate a notable increase in these serious conditions during the COVID-19 era, suggesting a need for better risk management and treatment guidelines for affected patients.