Publications by authors named "Alison R Rep"
Article Synopsis
- VPS4, an AAA-type ATPase, is recruited to viral assembly complexes in human cytomegalovirus infections to help with membrane constriction and fission, interacting with the viral protein pUL71.*
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- A specific peptide motif within pUL71 is crucial for this interaction, predicted to bind to VPS4A similarly to how cellular ESCRT-III components interact.*
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- This recruitment of VPS4A by pUL71 isn't essential for viral replication or morphogenesis, suggesting that its function remains unclear and highlighting a novel viral strategy that mimics cellular processes.*
