Extended-Spectrum β-Lactamase-Producing in Dogs from Cape Verde and São Tomé and Príncipe: Implications for Public Health.

Antimicrobial resistance is a growing global threat, with surveillance providing essential information to control its spread and support rational treatment strategies. , a member of the Gram-negative Enterobacteriaceae family, frequently develops resistance mechanisms. This study analyzed 195 rectal swabs from companion and stray dogs in Santiago and São Nicolau (Cape Verde) and São Tomé and Príncipe, sampled during a neutering and deworming campaign conducted by Veterinary Without Borders Portugal, to detect extended-spectrum β-lactamase (ESBL)-producing bacteria.

In Vivo Effect of a Nisin-Biogel on the Antimicrobial and Virulence Signatures of Canine Oral .

Periodontal disease is a relevant oral disease in dogs and nisin-biogel has been previously proposed to be used in its control. , as inhabitants of the oral cavity with a high genetic versatility, are a reliable bacterial model for antimicrobial studies. Our goal was to evaluate the in vivo influence of the long-term dental application of the nisin-biogel on the virulence and antimicrobial signatures of canine oral .

ESBL-Positive Enterobacteriaceae from Dogs of Santiago and Boa Vista Islands, Cape Verde: A Public Health Concern.

Antimicrobial resistance is a public health threat with an increasing expression in low- and middle-income countries such as Cape Verde. In this country, there is an overpopulation of dogs, which may facilitate the spread of resistant bacteria, including extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae. To clarify the role of dogs as reservoirs for the dissemination of this bacterial group, 100 rectal swab samples were collected from confined (n = 50) and non-confined (n = 50) dogs in Santiago and Boa Vista Islands, Cape Verde.

Determination of 14 trace elements in blood, serum and urine after environmental disaster in the Doce River basin: Relationship between mining waste and metal concentration in the population.

Background: Exposure to chemical substances after an environmental disaster can cause both toxic effects and changes in the health status of people who live in or have proximity to environments of this nature, so that the concern with populations is growing.

Methods: In this cross-sectional study, blood, serum and urine samples were collected from 100 volunteers from Santo Antônio do Rio Doce, eight from Ilha das Pimentas and 50 from the control group; and analyzed by inductively coupled plasma mass spectrometry for biomonitoring of Al, As, Ba, Cd, Co, Cu, Cr, Fe, Hg, Mn, Ni, Se, Pb, Zn. In addition, a comprehensive questionnaire was applied to collect demographic and socioeconomic information, as well as lifestyle.

E-inclusion: Beyond individual socio-demographic characteristics.

The changing demographic structure of the population, resulting in unparalleled growth of the elderly population, means that e-inclusion of this population group is considered to be a social and political priority in the context of the Information Society. Most research studies have only considered individual variables -such as age, gender, education, income and health- in the explanatory models of e-inclusion of senior citizens, while ignoring macro variables, such as the welfare systems and public policies in each country. Simultaneously, most studies focus on small-scale samples, lack international comparisons and do not consider the combined effect of several variables that influence Internet use.

Informal support in Portugal by individuals aged 50.

In Portugal, individuals aged 50+ have an important role in the provision of co-residential care. This study aimed to rank Portugal relative to 15 European countries with regard to the prevalence of co-residential care (daily or almost daily personal care), and extra-residential help/care (household help and/or personal care) provided by individuals aged 50+, and determine the factors associated with the provision of these types of support in the Portuguese context. The study used data from the SHARE wave 4 project (2010-2011) and was based on an analysis of variance and logistic regression models.

Changes in natural killer cell subpopulations over a winter training season in elite swimmers.

Immune changes and increased susceptibility to infection are often reported in elite athletes. Infectious episodes can often impair training and performance with consequences for health and sporting success. This study monitored the occurrence of episodes of upper respiratory symptoms (URS) and the variation in circulating NK cells, CD56(bright) and CD56(dim) NK cells subpopulations, over a winter swimming season.

Comparison of chronic graft-versus-host disease after transplantation of peripheral blood stem cells versus bone marrow in allogeneic recipients: long-term follow-up of a randomized trial.

In a previous multicenter phase III trial comparing peripheral blood stem cell transplantation (PBSCT) to bone marrow transplantation (BMT) from HLA-matched related donors, we found no statistically significant difference in the cumulative incidence of clinical extensive chronic graft-versus-host disease (GVHD) in the 2 groups. We have analyzed the results in more detail to determine whether the clinical characteristics of chronic GVHD after PBSCT might be distinct from those that occur after BMT. Clinical extensive chronic GVHD developed in 39 of 63 recipients of PBSCs and in 32 of 63 BM recipients who were alive and free of malignancy at day 100 after the transplantation.