Publications by authors named "Aliasghar Ghaderi"
Article Synopsis
- Candida parapsilosis is a major fungus contributing to nail infections, known for forming biofilms that resist standard antifungal treatments.
- This research focused on evaluating the effectiveness of the antifungal drug itraconazole against biofilms of C. parapsilosis, examining its ability to induce reactive oxygen species (ROS) that lead to cell death.
- The findings suggest that targeting ROS can enhance the effectiveness of antifungal therapy, particularly for stubborn cases of nail fungus, highlighting the potential of itraconazole as a key treatment option.
Introduction: Burn injuries lead to dysregulation of immune molecules, impacting cellular and humoral immune pathways. This study aims to determine the prediction of immune molecule activity during burn wound healing among elderly patients.
Methods: The current study utilized the Gene Expression Omnibus (GEO) database to extract the proper gene set.
Tinea incognita (TI) can mimic other dermatoses, presenting a diagnostic challenge for dermatologists. In some uncertain cases, it is crucial to accurately identify the causative agent using internal transcribed spacer (ITS) sequencing. The global issue of drug-resistant dermatophytosis is increasing, with Trichophyton (T.
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- - Recalcitrant dermatophytosis, mainly caused by Trichophyton indotineae, is becoming a significant issue globally, with a longer disease duration noted in patients infected by this strain.
- - The study identified various fungal isolates from infected skin samples, highlighting that 88.33% of T. mentagrophytes complex isolates were T. indotineae, and findings indicated that steroid use contributes significantly to the emergence of these infections.
- - For efficient diagnosis and treatment to counteract recalcitrant cases, direct skin sample PCR is recommended, due to its effectiveness in yielding reliable results similar to traditional methods.
Article Synopsis
- * A review of literature was conducted using databases like PubMed and Scopus, focusing on studies from 2006 to February 2023, to analyze the various clinical manifestations, prevalence, and causative agents of TI across different cases.
- * Results indicated that 50% of TI cases displayed eczema-like lesions, with other patterns such as psoriasis-like and rosacea-like also noted; to ensure accurate diagnosis, dermatologists must take a comprehensive patient history.
Prevalence of Delirium and Its Related Factors in Burn Patients; a Systematic Review and Meta-Analysis.
Arch Acad Emerg Med
November 2023
Introduction: Considering the importance of delirium disorder in burn patients and its complications, the present systematic review and meta-analysis aimed to determine the prevalence of delirium and its related factors in burn patients.
Methods: A comprehensive, systematic search was performed in different international electronic databases, such as Scopus, PubMed, and Web of Science, as well as Persian electronic databases such as Iranmedex, and Scientific Information Database (SID) using keywords extracted from Medical Subject Headings such as "Prevalence", "Delirium", and "Burns" from the earliest to the 17th of July, 2023.
Results: In total, 2,710 burn patients participated in ten original studies.
Pressure injury (PI), or local damage to soft tissues and skin caused by prolonged pressure, remains controversial in the medical world. Patients in intensive care units (ICUs) were frequently reported to suffer PIs, with a heavy burden on their life and expenditures. Machine learning (ML) is a Section of artificial intelligence (AI) that has emerged in nursing practice and is increasingly used for diagnosis, complications, prognosis, and recurrence prediction.
View Article and Find Full Text PDFThis systematic review aimed to examine the knowledge of caregivers regarding pressure ulcer (PU) prevention. A thorough, methodical search was conducted from the earliest date to February 1, 2023 using keywords extracted from Medical Subject Headings such as "Caregivers", "Knowledge", and "Pressure ulcer" in various international electronic databases such as Scopus, PubMed, Web of Science, and Persian electronic databases such as Iranmedex and Scientific Information Database. The quality of the studies included in this systematic review was evaluated using an appraisal tool for cross-sectional studies (AXIS tool).
View Article and Find Full Text PDFMesenchymal stem cells (MSCs) have the ability to migrate into tumor sites and release growth factors to modulate the tumor microenvironment. MSC therapy have shown a dual role in cancers, promoting or inhibiting. However, MSCs could be used as a carrier of anticancer agents for targeted tumor therapy.
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