Publications by authors named "Alexei Timofeev"
Stem Cell Res Ther
October 2024
Article Synopsis
- Mesenchymal stromal cells (MSCs) have significant potential in regenerative medicine but face challenges in classification, particularly for those from the pancreas; this study aims to better characterize pancreatic islet-derived MSCs (hPD-MSCs).
- The hPD-MSCs were isolated from donor islets and analyzed through various methods, confirming they possess key MSC features and can differentiate into fat and bone cells, with unique gene expression patterns compared to MSCs from other tissues.
- The findings reveal that hPD-MSCs share similarities with pancreatic stellate cells and identify specific genes related to pancreatic and neural functions, enhancing the understanding of their therapeutic potential.
