Publications by authors named "Alexandra A Frogoudaki"
Article Synopsis
- COVID-19 significantly affects coagulation in adult patients with congenital heart disease (ACHD), making them more susceptible to thromboembolic (TE) and bleeding complications.
- In a study from May 2020 to November 2021 involving nearly 2,000 ACHD patients, 1.5% experienced severe TE or bleeding events, which were linked to higher mortality rates and more advanced health conditions.
- Key risk factors for these complications included prior anticoagulation treatment, incidents of cardiac injury, and severity of the COVID-19 infection, with logistic regression confirming their independent associations with TE and bleeding risks.
COVID-19 in Adults With Congenital Heart Disease.
J Am Coll Cardiol
April 2021
Background: Adults with congenital heart disease (CHD) have been considered potentially high risk for novel coronavirus disease-19 (COVID-19) mortality or other complications.
Objectives: This study sought to define the impact of COVID-19 in adults with CHD and to identify risk factors associated with adverse outcomes.
Methods: Adults (age 18 years or older) with CHD and with confirmed or clinically suspected COVID-19 were included from CHD centers worldwide.
: We sought to assess in adult congenital heart disease (ACHD) patients the prognostic value of plasma galectin-3 (Gal-3) levels and systemic ventricular global longitudinal strain (SV GLS) as well as their association with NTproBNP and arrhythmogenesis. : We studied 58 patients (26 men, mean age 37 ± 16.8 years) with various congenital heart diseases.
View Article and Find Full Text PDFManagement of pregnancy in patients with complex congenital heart disease and pulmonary arterial hypertension has always been a challenge. We are presenting a patient with complex congenital heart disease and borderline pulmonary arterial hypertension who complicated with pulmonary embolism during pregnancy. ().
View Article and Find Full Text PDFTreatment of heart failure in adult congenital heart disease: a position paper of the Working Group of Grown-Up Congenital Heart Disease and the Heart Failure Association of the European Society of Cardiology.
Eur Heart J
May 2016
Atrial Fibrillation or Flutter During Pregnancy in Patients With Structural Heart Disease: Data From the ROPAC (Registry on Pregnancy and Cardiac Disease).
JACC Clin Electrophysiol
August 2015
Objectives: Atrial fibrillation (AF)/atrial flutter (AFL) during pregnancy in these women is associated with adverse outcome of pregnancy.
Background: The incidence, timing, and consequences of AF or AFL during pregnancy in patients with heart disease are not well known.
Methods: Between January 2008 to June 2011, 60 hospitals in 28 countries prospectively enrolled 1,321 pregnant women with congenital heart disease, valvular heart disease, ischemic heart disease, or cardiomyopathy in the ROPAC (Registry of Pregnancy and Cardiac Disease).
The purpose of this article is to address main clinical issues and the way to assess right ventricular (RV) function of adult patients with transposition complexes and systemic RV failure. Echo, cardiopulmonary exercise test, radionuclide ventriculography, cardiac magnetic resonance imaging, multislice computed tomography, and cardiac catheterization may be performed in adult patients with transposition complexes to evaluate clinical status and RV function. Echo is an everyday clinical tool that can give valuable information on RV function, tricuspid regurgitation, concomitant lesions, or postoperative complications.
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