Publications by authors named "Alex M Robbins"
Novel and unique rheumatoid factors cross-react with viral epitopes in COVID-19.
J Autoimmun
January 2024
Article Synopsis
- Rheumatoid factors (RFs) are antibodies linked to rheumatoid arthritis but can also appear in other diseases and infections, affecting immune responses.
- Recent research identified unique linear IgG epitopes targeted by RFs in COVID-19, which differ from those found in rheumatoid arthritis, showing disease-specific immune reactions.
- The COVID-19 RF demonstrated the ability to bind various viral peptides and IgG Fc due to a short peptide motif, suggesting potential mechanisms by which viral infections could lead to autoimmune conditions.