Publications by authors named "Alex D Vompe"

Article Synopsis
  • Pathogen transmission pathways are essential for studying infectious diseases, especially in ocean environments where they are difficult to track.
  • The study focuses on Seagrass Wasting Disease (SWD), which affects seagrass beds globally, and investigates how it spreads and its sensitivity to temperature through field and lab experiments.
  • Results indicate that SWD spreads through waterborne transmission rather than direct contact with infected plants, helping improve management and restoration of coastal ecosystems amid changing ocean conditions.
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Microbiomes are essential features of holobionts, providing their hosts with key metabolic and functional traits like resistance to environmental disturbances and diseases. In scleractinian corals, questions remain about the microbiome's role in resistance and resilience to factors contributing to the ongoing global coral decline and whether microbes serve as a form of holobiont ecological memory. To test if and how coral microbiomes affect host health outcomes during repeated disturbances, we conducted a large-scale (32 exclosures, 200 colonies, and 3 coral species sampled) and long-term (28 months, 2018-2020) manipulative experiment on the forereef of Mo'orea, French Polynesia.

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Inflammasome activation is regulated in part by the posttranslational modification of inflammasome proteins. Tyrosine phosphorylation is one possible modification. Having previously shown that the protein tyrosine kinase (PTK) inhibitor AG126 greatly inhibits inflammasome activation, we sought to uncover the target kinase.

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