Intelligent System for Automated Spheroid Segmentation Using Machine Learning.

Image segmentation is a crucial task of medical image processing, including the analysis of multicellular tumour spheroids (MTSs), a common in vitro model used in cancer research for drug screening. Accurate segmentation of MTSs images allows the extraction of the morphological features necessary for the evaluation of the efficacy of the treatment they undergo. This paper presents an artificial intelligence (AI)-based segmentation system for the analysis of RGB images of MTS using machine learning (ML) classifiers.

Automatic Segmentation of Multicellular Tumour Spheroids Images During Growing.

Image segmentation is an important topic in medical image processing. Multicellular tumour spheroids (MTS) are currently one of the most widely employed in vitro model for pre-clinical drug screening in cancer research. Assessing their growing requires the segmentation of images acquired at several time points.