Publications by authors named "Akhil Dondapati"

Purpose: We sought to identify predictors of successful revision carpal tunnel release (CTR) and compare long-term patient-reported outcomes to individuals who underwent primary CTR with no revision. We hypothesized that patients undergoing revision CTR would have worse patient-reported outcomes scores compared to primary CTR at 1-year follow-up.

Methods: We retrospectively compared 521 primary CTR and 57 revision CTR patients.

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Purpose: Dorsal bridge plating (DBP) can effectively treat complex distal radius fractures (DRFs); however, techniques for metacarpal fixation vary. The purpose of our study was to compare range of motion (ROM), grip strength, patient-reported outcomes, radiographic parameters, and complication rates between patients undergoing DBP with fixation to the second versus third metacarpal for DRFs.

Methods: We retrospectively analyzed 432 patients with DRFs.

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Introduction: This study sought to investigate the impact of the area deprivation index (ADI) on the treatment timeline from carpal tunnel syndrome (CTS) to carpal tunnel release (CTR). We hypothesize that increased social deprivation will correlate with increased time between care milestones from presentation to surgery.

Methods: This is a retrospective review of patients diagnosed with CTS who underwent CTR at a single academic institution.

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Purpose: The purpose of this study was to establish the impact of area deprivation index (ADI) on treatment timelines of patients with cubital tunnel syndrome (CuTS). We hypothesize that increased social deprivation will correlate with increased time between care milestones from presentation to surgery.

Methods: This is a retrospective study of patients diagnosed with CuTS who underwent surgical intervention at a single academic institution.

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Article Synopsis
  • This study investigates the occurrence of hand-related issues like carpal tunnel syndrome and trigger finger in patients after shoulder surgeries like arthroscopy and arthroplasty.
  • Researchers analyzed data from over 12,000 patients, finding a significant number developed these hand pathologies within one year post-surgery compared to control groups.
  • The results indicated that both arthroscopy and arthroplasty procedures increased the risk of hand-related conditions, with shoulder arthroplasty showing a higher risk than arthroscopy.
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Purpose: Carpal tunnel syndrome is the most common peripheral nerve compressive neuropathy in clinical practice. Patients who fail nonsurgical management are indicated for carpal tunnel release (CTR), which can be performed open or endoscopically. Efforts have been made to utilize local anesthesia instead of monitored anesthesia care (MAC) for endoscopic release.

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Purpose: Distal radius fractures (DRFs) indicated for operative intervention are most commonly treated with volar-locked plating (VLP); however, dorsal bridge plating (DBP) has been used as an alternative fixation method. The purpose of this study was to use a propensity score to match and compare the radiographic and clinical outcomes of patients undergoing isolated VLP or DBP for DRFs.

Methods: We performed a retrospective, propensity score-matched analysis of patients undergoing isolated VLP or DBP treatment for isolated DRFs from 2015 to 2022 at a single level-1 trauma center.

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Objectives: Identification of modifiable comorbid conditions in the preoperative period is important in optimizing outcomes. We evaluate the association between such risk factors and postoperative outcomes after upper extremity surgery using a national database.

Methods: The National Surgical Quality Improvement Program (NSQIP) 2006-2016 database was used to identify patients undergoing an upper extremity principle surgical procedure using CPT codes.

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Objectives: The purpose of this study is to evaluate the outcomes of operatively treated Mason Type III radial head fractures. Additionally, this project seeks to assess efficacy of PROMIS in evaluating post-operative outcomes for this patient population.

Methods: A total of 143 patients who underwent operative treated Mason Type III radial head fractures were analyzed retrospectively.

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Background: Distal radius fractures with severely osteoporotic bone or articular comminution can provide challenges to fixation with traditional volar locked plating alone. The purpose of this study was to evaluate the clinical, radiographic, and patient reported outcomes of patients undergoing distal radius fixation with volar locked plating and adjunctive dorsal bridge plating.

Methods: We retrospectively identified 16 patients with distal radius fractures who underwent our preferred surgical technique for fixation.

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Introduction: The purpose of our study is to analyze the outcomes of traumatic posterolateral elbow dislocations using patient-reported outcomes measurement information system (PROMIS). We hypothesized that physical function (PF) and upper extremity (UE) scores in PROMIS will significantly improve over six months of follow-up and correlate with a positive change in the patient-acceptable symptom state (PASS).

Methods: This is a seven-year retrospective study of 165 consecutive adult patients with traumatic posterolateral elbow dislocations.

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Article Synopsis
  • The study aims to evaluate outcomes of Mason type I radial head fractures treated non-operatively, focusing on the significance of Patient-Reported Outcomes Measurement Information System (PROMIS) as a tracking tool for patient recovery.
  • Researchers analyzed data from 527 patients over a year, looking at various PROMIS scores relating to physical function, upper extremity performance, pain interference, and depression at different time points post-injury.
  • Results showed significant improvements in PROMIS upper extremity and pain interference scores at six weeks and six months, but overall physical function did not show notable changes, highlighting the complexities of patient recovery and the importance of tracking specific outcomes.
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  • Neuromodulation is becoming a popular method for managing chronic pain, with new waveforms like high-frequency 10 kHz spinal cord stimulation (SCS) showing better outcomes than traditional methods.
  • A study reviewed data from 21 patients who experienced chronic pain, finding that 85.7% reported pain relief after the procedure and significant reductions in pain scores 12 months post-op.
  • The findings suggest that high-frequency SCS is effective for various chronic pain conditions and supports its use as a first-line treatment option in clinical settings.
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While CDD directly to the CSF can provide a constant delivery of the dopaminergic drug resulting in a more stable treatment effect without the limitations of traditional oral therapy without peripheral effects, it is still young and longitudinal data is lacking. These experimental therapies show promise and further investigation into their efficacy and safety could extend the frontiers for management of PD.

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There is increasing interest in using alpha particle emitting radionuclides for cancer therapy because of their unique cytotoxic properties which are advantageous for eradicating tumor cells. The high linear energy transfer (LET) of alpha particles produces a correspondingly high density of ionizations along their track. Alpha particle emitting radiopharmaceuticals deposit this energy in tissues over prolonged periods with complex dose rate patterns that depend on the physical half-life of the radionuclide, and the biological uptake and clearance half-times in tumor and normal tissues.

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Article Synopsis
  • * Researchers are looking into synthetic peptide-based nanostructures as alternatives to direct angiogenic protein delivery due to their prolonged effectiveness and enhanced presentation of functional elements.
  • * The study explores methods to incorporate these angiogenic peptide mimics into self-assembled peptide scaffolds for use in regenerating damaged tissue.
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