SEEG-guided radiofrequency thermocoagulation of the epileptogenic networks: Its utility for both treatment and validation for localizing epileptogenic networks.

Introduction: Stereoelectroencephalography-guided radio-frequency thermo coagulation (SEEG-RFTC) is a minimally invasive technique whereby radiofrequency-thermocoagulation is performed using SEEG electrodes, following recording and stimulation. It helps to disconnect/disrupt or ablate the epileptogenic networks, and provides both therapeutic and diagnostic abilities.

Methods: Retrospective study (2016-2024).

Temperature- and time-dependent degradation of mouse tissue proteins: insights into RNA-binding protein stability mass spectrometry.

In proteomics research, samples are frequently stored at -20 °C and -80 °C for extended periods, and assessing protein stability under these conditions is essential. We evaluated protein stability in healthy and diseased mice liver tissues stored at 4 °C, -20 °C, and -80 °C for 0, 7, 30, 90, and 180 days. A 10% variation in protein concentrations (by day 90, < 0.

Xenomonitoring and Molecular Characterization of from in Alappuzha, Kerala, India.

Lymphatic filariasis is a major public health problem known for its disfiguring and debilitating effects. Alappuzha district in Kerala has been a hotspot for Brugian and Bancroftian filariasis. The efforts to combat Brugian filariasis in this region about two decades earlier led to notable decline in vector density and interruption of disease transmission.