Publications by authors named "Aishwarya Chohan"

Background: Post-acute sequelae of COVID-19 (PASC) or Long COVID is a post-viral complication of SARS-CoV-2 infection, causing ongoing symptoms and impaired function over a prolonged period of time. There is limited understanding of how the signs and symptoms of Long COVID/PASC affect patients' lives and how to measure them, which is essential when developing care strategies. This study aimed to develop and evaluate the content validity for a novel patient-reported outcome (PRO) instrument in Long COVID/PASC through qualitative research, which was informed by the patient experience of Long COVID/PASC and both patient and clinician input.

View Article and Find Full Text PDF

Background: Chronic hepatitis D (CHD) is the most severe form of viral hepatitis, which results in accelerated progression to cirrhosis and poor prognosis compared with other hepatitis infections, impacting patients' health-related quality of life (HRQoL). To adequately capture patient perspectives of new hepatitis D virus (HDV) treatments in clinical trials, patient-reported outcome (PRO) measures that are valid and assess key concepts relevant to the patient are needed. This study aimed to explore the patient experience of CHD and evaluate the content validity of the Hepatitis Quality of Life Questionnaire (HQLQv2) and the Fatigue Severity Scale (FSS) for use in an HDV population.

View Article and Find Full Text PDF
Article Synopsis
  • Several existing COA tools for assessing Sjögren's disease symptoms lack a comprehensive evaluation of health-related quality of life (HRQoL); this study aimed to create a new patient-reported outcome (PRO) instrument for better assessment in clinical settings and trials.
  • The development of the Sjögren's Related Quality of Life (SRQoL) included qualitative interviews with patients to capture their experiences and establish the content validity of the tool and associated severity assessment items (PGI-S and PGI-C).
  • After interviewing 20 participants, eight domains of HRQoL impact were identified, including emotional well-being, sleep, daily activities, cognition, physical functioning, social/family dynamics, work, and sexual functioning, signaling the SRQo
View Article and Find Full Text PDF

Background: Loneliness during adolescence has adverse consequences for mental health, education and employment outcomes. Yet, we know little about common correlates of loneliness among adolescents, making intervention work difficult.

Aims: In this study, we (1) explore individual-, school- and country-level correlates of loneliness to help identify potential intervention targets, and (2) examine the influence of loneliness on academic performance.

View Article and Find Full Text PDF