Design, Ssynthesis and Ddocking study of 1,2,3-triazole incorporated benzoxazole-oxazole derivatives and evaluation as potential anticancer agents.

The study reports the design and synthesis of a new library of triazole in-corporated benzoxazole oxazole compounds (11a-j) and their in vitro cytotoxic activity evaluation. The structural reliability of the synthesized compounds was confirmed by H NMR, C NMR, and mass spectral data. We have selected ER-α and CDK2 proteins for molecular docking study of the active compounds to examine their binding interactions.