In vivo submillimeter diffusion MRI dataset of 9 macaque brains curated for tractography.

In vivo diffusion magnetic resonance imaging (MRI) is critical to access detailed information about the brain microstructure and connectivity. In non-human primates (NHPs), especially macaque monkeys, such acquisitions should be carried out at a submillimeter resolution to enable accurate tractography, i.e.

Automated lever task with minimum antigravity movement for rats with cervical spinal cord injury.

Background: Although there is currently no cure for paralysis due to spinal cord injury (SCI), the highest treatment priority is restoring arm and hand function for people with cervical SCI. Preclinical animal models provide an opportunity to test innovative treatments, but severe cervical injury models require significant time and effort to assess responses to novel interventions. Moreover, there is no behavioral task that can assess forelimb movement in rats with severe cervical SCI unable to perform antigravity movements.

Brain-Computer-Spinal Interface Restores Upper Limb Function After Spinal Cord Injury.

Brain-computer interfaces (BCIs) are an emerging strategy for spinal cord injury (SCI) intervention that may be used to reanimate paralyzed limbs. This approach requires decoding movement intention from the brain to control movement-evoking stimulation. Common decoding methods use spike-sorting and require frequent calibration and high computational complexity.

Ultra-Capacitive Carbon Neural Probe Allows Simultaneous Long-Term Electrical Stimulations and High-Resolution Neurotransmitter Detection.

We present a new class of carbon-based neural probes that consist of homogeneous glassy carbon (GC) microelectrodes, interconnects and bump pads. These electrodes have purely capacitive behavior with exceptionally high charge storage capacity (CSC) and are capable of sustaining more than 3.5 billion cycles of bi-phasic pulses at charge density of 0.