Publications by authors named "Adrian O Vaduva"
: Tooth bleaching is a widely requested aesthetic procedure in modern dentistry. However, the structural effects of high-concentration peroxide-based bleaching agents on enamel remain insufficiently understood. This study aims to evaluate and compare the effects of three in-office bleaching agents-Opalescence Boost (40% hydrogen peroxide [HP]), Opalescence Quick (45% carbamide peroxide [CP]), and BlancOne Ultra + (35% hydrogen peroxide [HP])-on enamel surface characteristics and color change using confocal laser scanning microscopy (CLSM) and spectrophotometric analysis.
View Article and Find Full Text PDFBackground And Objectives: We aimed to assess the significance of sex and age compared to other clinical-pathological parameters in colorectal cancer (CRC).
Materials And Methods: Our study included a retrospective approach to CRC patients who underwent surgery at the 'Pius Brinzeu' County Clinical Emergency Hospital in Timisoara (PBECCHT), Romania. The analyzed parameters were: patient age and sex, tumor location, histological type, differentiation grade (G), extent of tumor (pT), lymph-node status (pN), distant metastasis status (pM), and lymphovascular invasion (LVI).
Aim: The aim of our study was to assess the therapeutic effects of platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) in an animal knee lesion complex associating a large osteochondral defect and meniscal defect resulted from partial meniscectomy, a clinical situation that occurs quite often in orthopedic practice.
Materials And Methods: Twenty-one male rabbits were included in the study, and all underwent initial surgery on the right knee to create the osteochondral defect on the internal femoral condyle, and remove the anterior horn of the internal meniscus, simulating a clinical situation. Rabbits were separated in three study groups: control, PRP group, in which three PRP injections were administered, and BMAC group, in which one single BMAC injection was administered.
Article Synopsis
- The study explored the effectiveness of incorporating 3D virtual models in teaching anatomic pathology to medical students, comparing it to traditional formalin-stored specimens.
- Despite students finding the 3D models subjectively better, their performance on assessments was poorer with the new method compared to the traditional approach.
- The research suggests that increased familiarity and integration of novel teaching tools could enhance learning outcomes for students who are more accustomed to digital resources.
Monoamine oxidase is a source of oxidative stress in obese patients with chronic inflammation .
Can J Physiol Pharmacol
September 2019
Article Synopsis
- * The study focused on samples from obese patients during surgery, showing that the MAO-A isoform was prevalent in both fat and blood vessel tissues, correlating with higher levels of reactive oxygen species (ROS) and impaired blood vessel function.
- * Using a MAO-A inhibitor improved blood vessel function and reduced ROS production, indicating that targeting MAO-A could be a potential strategy for addressing complications related to obesity and inflammation.
Background And Aim: The outcome for some colorectal cancer patients correlates poorly with classical prognostic factors, like tumor stage. Tumor budding (TB) is a promising and intensely studied new prognostic factor. We aimed to evaluate the reliability of bud counting on Hematoxylin-Eosin (HE)-stained and immunohistochemically (IHC)-stained scanned slides.
View Article and Find Full Text PDFOxidative stress is a culprit responsible for the development of acute and chronic kidney diseases. We aimed to establish a working model for the dynamic in vivo assessment of reactive oxygen species (ROS) production in rat kidney. A randomized controlled study was performed in 36 adult male Wistar rats subjected to unilateral urinary obstruction (UUO) via ureteral ligation and compared to SHAM controls.
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