Publications by authors named "Adeline Normand"
Article Synopsis
- - A study reported on five patients with myeloid neoplasms who experienced liver complications, with liver biopsies showing that their liver sinusoids were blocked by platelet clumps and evidence of extramedullary hematopoiesis.
- - The group included four men and one woman, ages 50 to 82, diagnosed with various haematological disorders, such as myeloproliferative neoplasms and chronic myelomonocytic leukaemia.
- - All patients had severe liver issues, leading to different causes of death within 2 to 23 months post-biopsy, including acute myeloblastic leukaemia and portal hypertension, suggesting that microthromboses could lead to liver complications
Article Synopsis
- Immunotherapy that uses the body's immune system is becoming popular in treating blood cancers like mantle cell lymphoma (MCL), but there's little understanding of immune cell behavior in MCL patients' lymph nodes and bone marrow.
- The study utilized a technique called RT-MLPA to analyze gene expression in MCL patients at diagnosis and relapse, focusing on immune-related genes to gain insights into tumor aggressiveness and immune response.
- Results showed that aggressive MCL forms had increased macrophage-related gene expression but lower T-cell markers, which could help differentiate between patient groups and guide personalized treatment approaches.
Introduction: The motivations of medical students for Pathologic Anatomy are little known although they can strongly influence their academic performance. Our work focused on the analysis of the relationship between performance and motivation for Pathologic Anatomy.
Materials And Methods: Second-year students (n=268) from the University of Nantes were contacted to complete a motivation questionnaire and to provide indicators of performance and attendance.