Novel Perineural Pathways and The Dynamics of Simian Immunodeficiency Virus-Infected Macrophage Trafficking Out of the Central Nervous System.

A challenge to eradicate HIV is the CNS reservoir and unknown mechanisms-pathways by which infected macrophages can exit. We used intracisternal (i.c.

Resolving Inflammation: The Impact of Antiretroviral Therapy on Macrophage Traffic In and Out of the CNS.

The effect of antiretroviral therapy (ART) and therapy interruption on myeloid cell traffic out of the central nervous system (CNS) with human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infection are understudied. Using intracisternal (i.c.